[Quantum transitions between states and cosmophysical fluctuations].

An explanation of the appearance of the reproducible fine structure of the histograms corresponding to different processes from simple chemical reactions to radioactive decays is developed. Earlier this explanation was reduced to extremely strong influence of small changes between energy levels of a quantum system under study and its environment on the transition probability of the system (chemical reaction, radioactive decay, e.t.

[Sulfur ligands within the cluster formations of copper at its strong'binding sites on the cytoplasmic membrane of Escherichia coli].

The analysis of the saturation curves of ESR signals revealed a decrease in the relaxation rate of fast-relaxation Cu(I) complexes on the cytoplasmic membrane of E. coli after the interaction of these bacteria with low concentrations of SH-reagents. It was concluded that the observed changes are associated with the reorganization of Cu clusters due to the binding of SH groups incorporated into the clusters N-ethylmaleimide or Ag(I).

[Change in certain physical characteristics of cells at various stages of the cell cycle].

Experiments on semisynchronized cultures of animal and plant cells, performed in our laboratory approximately 30 years ago, have demonstrated that there exist regular changes of certain physical parameters of the cells during the cell cycle. In particular on yeast cultures there has been observed the appearance of specific electron paramagnetic resonance (EPR) signals with simultaneous change of the static magnetic susceptibility of the cultures in the period immediately preceding the beginning of the intensive budding. On chlorella cultures grown at certain regimes of light and darkness it is possible to observe characteristic changes of the kinetics of the photoconduction signal at the frequency of 10 HHz (SHR-photoconduction).

[Parametric resonance as a possible mechanism of action of superlow concentrations of biologically active substances at the cellular and subcellular levels].

At extra-low concentrations of biologically active substances (BAS) the limiting stage of processes determining their action at cell and sub-sell levels is BAS diffusion to the cell surface. According to proposed parametric resonance model the BAS activity extreme values are to be observed when the reciprocal values of collision frequency between BAS molecules and cell surface coincide (by order of magnitude) with the characteristic times of conformational relaxation of certain macromolecular structures responsible of the studied process. The calculation results do not contradict the experimental data.

[RNA secondary structure dynamics and genetic vector symmetry].

The sequence of nucleotides in a single-stranded RNA molecule is represented by a complex vector, whose k-th component corresponds to the k-th base of the sequence ordered in the 5'3' direction. An analysis of the proposed formalisms permits to predict a new type of reversible conformational transitions between the secondary structure patterns of RNA which may have an oscillatory character. A possible experimental approach based on the ESR technique for recording and time-scale estimation of these transitions is proposed.