Publications by authors named "L A Bianchi"
The increasing interest in hadron therapy has heightened the need for accurate and reliable methods to assess radiation quality and the biological effectiveness of particles used in treatment. Microdosimetry has emerged as a key tool for this, demonstrating its potential, reliability, and suitability. In this context, solid-state microdosimeters offer technological advantages over traditional Tissue-Equivalent Proportional Counters, and recent advancements have further improved their performance and reliability.
View Article and Find Full Text PDFRadiofrequency ablation (RFA) is a minimally invasive procedure that utilizes localized heat to treat tumors by inducing localized tissue thermal damage. The present study aimed to evaluate the temperature evolution and spatial distribution, ablation size, and reproducibility of ablation zones in ex vivo liver, kidney, and lung using a commercial device, i.e.
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- The autonomic nervous system (ANS) plays a key role in the health benefits associated with whole-body cold stimulation (WBC), but understanding its effects is complicated due to varying methodologies and data interpretation challenges.
- A study involved 23 subjects with obesity undergoing 10 WBC sessions, with heart rate variability (HRV) analyzed to assess changes in cardiac autonomic control (CAR) at two different temperatures.
- Results indicated that both temperature treatments significantly improved CAR, as shown by an increase in the Autonomic Nervous System Index (ANSI) and enhanced heart rate variability over the course of the treatment.
Actinic keratosis (AK) is a precursor to invasive squamous cell carcinoma, making early diagnosis and treatment essential to prevent progression. Among available therapeutic options, nicotinamide (NAM) has shown potential in reducing AK progression. NAM is a precursor of nicotinamide adenine dinucleotide (NAD), which activates sirtuin (SIRT)1, a protein with anti-cancer properties.
View Article and Find Full Text PDFIntroduction: Fungi, including , may be a trigger or exacerbate psoriasis, especially in difficult to treat (DTT) areas, through the activation of IL-17/23 axis.
Methods: In this study, seventy patients with DDT psoriasis were enrolled to evaluate species and/or other opportunistic fungi colonization rate at baseline (T0) and the impact of apremilast on fungal load, clinical outcome, serum cytokine levels and biochemical serum profile of patients after 16, 24 and 52 weeks of treatment.
Results: In our population, 33 (47%) patients were colonized by spp.