Childhood exposure to social disadvantage is a major risk factor for psychiatric disorders and poor developmental, educational, and occupational outcomes, presumably because adverse exposures alter the neurodevelopmental processes that contribute to risk trajectories. Yet, given the limited social mobility in the United States and other countries, childhood social disadvantage is frequently preceded by maternal social disadvantage during pregnancy, potentially altering fetal brain development during a period of high neuroplasticity through hormonal, microbiome, epigenetic, and immune factors that cross the placenta and fetal blood-brain barrier. The current study examines prenatal social disadvantage to determine whether these exposures in utero are associated with alterations in functional brain networks as early as birth.
View Article and Find Full Text PDFThe Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds repors that will prove useful for clinicians practicing at the interface of medicine and psychiatry.
View Article and Find Full Text PDFIntroduction: The proactive management of spina bifida (SB), especially of its severe form, myelomeningocele (MMC), has contributed to decreasing chronic kidney disease (CKD). The objective of this study is to present the evolution of 5-year-old patient with MMC followed from birth with a proactive approach.
Material And Methods: This retrospective study included 55 cases with MMC of up to 5 years of age.
Acid mine drainage occurs due to the chemical and microbiological oxidation of sulfide minerals and can be a source of potentially toxic elements contamination of groundwater and surface water. The objective of this study was to identify microorganisms involved in sulfide oxidation in the tailings of a Bahia Gold Belt mine (Brazil). Samples of solids and water were collected at the mine tailings dam and characterized.
View Article and Find Full Text PDFSouring in oil fields occurs mainly due to the activity of sulfate reducing bacteria (SRB). Most of the studies on SRB are performed using upflow packed-bed reactors that have a limitation to describe the region close to the injection wells in oil fields, which is characterized by void and saturated porous bed regions. Here, it is described the design and operation of a pilot scale system to investigate the SRB activity, inhibition and control in oil fields.
View Article and Find Full Text PDF