[Trend in the emergence of flea imagoes from cocoons in the nests of a mountain gopher (Spermophilus musicus) in the central Caucasian highland natural focus of plague].

The results of observations of a trend in the emergence of flea imagoes from cocoons in the nests of mountain gopher (Spermophilus musicus) (Elbrus region) confirm that the dominant species: Citellophilus tesquorum elbrusensis and Ctenophthalmus golovi golovi have two generations. Emergence of first-generation imagoes from cocoons is recorded in July-August in the nests where the grophers constantly inhabit in May-June. These are brood-rearing and other summer nests and, to a lesser degree, former wintering ones.

[Characteristics of basic phenoperiods of fleas--parasites of small and mountain susliks in the Northern Caucasus].

For the fleas of sousliks of the North Caucasus, whose imagoes are in nature throughout a year, the authors identify three phenoperiods: 1) a phenoperiod of gonotropic activity (in fleas that have two generations, it consists of a phenophase of multiplication of second-generation imagoes of a previous year and of that of multiplication of first-generation imagoes of a current year; 2) a phenoperiod of preparation for gonotropic hibernation; 3) a phenoperiod of gonotropic hibernation. In the fleas that exist as imagoes for a short period of a year, in spring and summer, the authors single out two phenoperiods: imaginal and preimaginal that consists of a phenophase of flea existance at the stages of metamorphosis and a phenophase of imago cocooning.

[The participation of RNA synthesis in the process of the acquisition and retention of conditioned reflexes (a study using antifeins)].

RNA-synthesizing activity of neuronal nuclei in the neocortex of rats increases after the termination of conditioning depending on the degree of learning. RNA synthesis shifts induced by propylnorantifein and the demethylated derivatives of ethylnorantifein are correlated only with the influence of the drugs on the retention but not the learning. Participation of RNA synthesis by the neurons of the neocortex in the mechanisms of long-term memory is discussed.

[Participation of protein synthesis in brain cell structures in the action of antifeins on long-term memory].

Incorporation of 3H-leucine into proteins of rat brain cell structures during application of antifeins (compounds of alternative action on memory processes) has been studied. No correlation was observed between changes in protein synthesis in nuclei, mitochondria, components of endoplasmic reticulum and memory effects of ethyl-, allyl- and propylnorantifeins. Only M1 and M2-demethylated structural analogs of ethylnorantifeins (exerting the most effective action on RNA synthesis and retention of conditional reflexes) enhanced the synaptosomal protein synthesis.

[Effect of HMG proteins and their phosphorylated forms on the process of transcription in neuronal nuclei of the rat brain (data from an immunochemical analysis)].

It was found that chromatin transcription in the neuronal nucleus of rat brain is inhibited by antisera to proteins HMG 14, HMG 17 and HMG 2. It is known that chromatin transcription of the neuronal nucleus and phosphorylation of chromosomal proteins are activated by etimizol. The phosphorylation of chromosomal proteins activated by etimizol is inhibited by the antiserum to HMG 14 (but not to HMG 17).