Spontaneous bone bed formation in pediatric cochlear implantation is associated with duration of implantation.

Objectives: This study investigated the long-term postoperative spontaneous formation of a bone bed in pediatric cochlear implant patients for whom no bone bed was drilled during the surgery.

Methods: A cross-sectional observational study of skull thickness under and on the edges of the cochlear implant receiver/stimulator in children with computed tomography (CT scan) ≥6 months after implantation was performed. In total, 37 pediatric patients from a single tertiary center underwent cochlear implantation without bone bed drilling and with screw fixation of the receiver/stimulator.

[Effect of resveratrol, carnitin, quercetin and aromatic amino acids on the xenobiotic metabolising and antioxidant enzymes in the liver during obesity in rats with different genotypes].

The use of minor biologically active substances (BAS) in specialized products is one of the promising areas in the diet therapy for obesity and other alimentary-dependent diseases (metabolic syndrome, type 2 diabetes mellitus, etc.). The effects of the BAS in patients are often ambiguous, depending on a number of factors, one of which is the state of the organism enzyme systems (enzymes of xenobiotic metabolism and antioxidant defense), the patient's genotype, and many others.