Publications by authors named "L A A Galal"
The protozoan Toxoplasma gondii is a ubiquitous and highly prevalent parasite that can theoretically infect all warm-blooded vertebrates. In humans, toxoplasmosis causes infections in both immunodeficient and immunocompetent patients, congenital toxoplasmosis, and ocular lesions. These manifestations have different degrees of severity.
View Article and Find Full Text PDFGenotyping of European Toxoplasma gondii strains by a new high-resolution next-generation sequencing-based method.
Eur J Clin Microbiol Infect Dis
February 2024
Purpose: A new high-resolution next-generation sequencing (NGS)-based method was established to type closely related European type II Toxoplasma gondii strains.
Methods: T. gondii field isolates were collected from different parts of Europe and assessed by whole genome sequencing (WGS).
Article Synopsis
- Carbapenem resistance poses a significant public health risk in sub-Saharan Africa, particularly at the intersections of human, animal, and environmental factors, as shown in a study conducted in Djibouti City.
- The study analyzed 1650 samples, including urine, hospital specimens, livestock feces, fish, and water, revealing a low overall prevalence of 1.9% CP-GNB, with higher rates in fish (11.7%) and water (10%).
- Genome sequencing identified key bacterial species associated with resistance and indicated the presence of epidemic clones, suggesting horizontal gene transfer plays a role in the spread of carbapenem resistance across different environments.