Effects of Input Parameter Range on the Accuracy of Artificial Neural Network Prediction for the Injection Molding Process.

Artificial neural network (ANN) is a representative technique for identifying relationships that contain complex nonlinearities. However, few studies have analyzed the ANN's ability to represent nonlinear or linear relationships between input and output parameters in injection molding. The melt temperature, mold temperature, injection speed, packing pressure, packing time, and cooling time were chosen as input parameters, and the mass, diameter, and height of the injection molded product as output parameters to construct an ANN model and its prediction performance was compared with those of linear regression and second-order polynomial regression.

Innovative Injection Molding Process for the Fabrication of Woven Fabric Reinforced Thermoplastic Composites.

Woven fabric reinforced thermoplastic composites have been gaining significant attention as a lightweight alternative to metal in various industrial fields owing to their high stiffness and strength. Conventional manufacturing processes of woven fabric reinforced thermoplastic composites can be divided into two steps: first, the manufacturing of intermediate material, known as prepreg; then, the formation of the final products from the prepregs. This two-step process increases the manufacturing cost and time of the final composite products.

An Experimental Study on Color Shift of Injection-Molded Mobile LGP Depending on Surface Micropattern.

In the display industry, the LCD backlight unit (BLU) module is variously used in mobile phones, notebook computers, monitors, and TVs. The light guide plate (LGP), which is one of the core parts of a BLU, is getting bigger and thinner consistently. Conventional injection methods and injection processes like injection compression molding (ICM) are becoming more complex and harsher with high-speed injection at high mold and melt temperatures.

Computational Fluid Dynamics of Intracranial and Extracranal Arteries using 3-Dimensional Angiography: Technical Considerations with Physician's Point of View.

We investigate the potentials and limitations of computational fluid dynamics (CFD) analysis of patient specific models from 3D angiographies. There are many technical problems in acquisition of proper vascular models, in pre-processing for making 2D surface and 3D volume meshes and also in post-processing steps for display the CFD analysis. We hope that our study could serves as a technical reference to validating other tools and CFD results.

Effects of degumming conditions on electro-spinning rate of regenerated silk.

Electro-spun silk webs are potentially good candidates as tissue engineering scaffolds owing to their good bio- and cyto-compatibility. However, the low fabrication rate of electro-spun silk mats has been one of the obstacles in the mass production of such nanofibrous silk mats in applications to the biomedical field. In this study, the effects of degumming ratio and silk concentration on the electro-spinning process were investigated by using regenerated silk with different residual sericin contents and different silk concentrations in terms of the morphology and structure of the electro-spun silk web.

Computational modeling with fluid-structure interaction of the severe m1 stenosis before and after stenting.

Purpose: Image-based computational models with fluid-structure interaction (FSI) can be used to perform plaque mechanical analysis in intracranial artery stenosis. We described a process in FSI study applied to symptomatic severe intracranial (M1) stenosis before and after stenting.

Materials And Methods: Reconstructed 3D angiography in STL format was transferred to Magics for smoothing of vessel surface and trimming of branch vessels and to HyperMesh for generating tetra volume mesh from triangular surface-meshed 3D angiogram.

Effect of degumming condition on the solution properties and electrospinnablity of regenerated silk solution.

The application of silk on tissue engineering scaffolds has been studied intensively because silk has an electrospinning technique using a good blood compatibility, excellent cytocompatibility and biodegradability. Silk consists of two polymers, fibroin and sericin. In spite of importance of sericin, most studies were focused on the fibroin only and the effect of residual sericin on the electrospinning performance of silk has not been considered.

A bioreducible polymer for efficient delivery of Fas-silencing siRNA into stem cell spheroids and enhanced therapeutic angiogenesis.

This paper describes a bioreducible polymer for efficient delivery of Fas-silencing small interfering RNA (Fas siRNA) into human mesenchymal stem cells (hMSCs). The genetically modified hMSCs could be formulated as spheroids with enlarged sizes (≥ 800 μm in diameter) to enhance their angiogenic efficacy. The Fas siRNA delivered into the cytoplasm of hMSCs via the bioreducible polymer could efficiently inhibit Fas expression, leading to effective inhibition of hypoxia-induced apoptosis in the core of an enlarged spheroid of hMSCs.

Computational flow dynamics of the severe m1 stenosis before and after stenting.

Purpose: Computational flow dynamic (CFD) study has not been widely applied in intracranial artery stenosis due to requirement of high resolution in identifying the small intracranial artery. We described a process in CFD study applied to symptomatic severe intracranial (M1) stenosis before and after stenting.

Materials And Methods: Reconstructed 3D angiography in STL format was transferred to Magics (Materialise NV, Leuven, Belgium) for smoothing of vessel surface and trimming of branch vessels and to HyperMesh (Altair Engineering Inc.

High shear stress at the surface of enhancing plaque in the systolic phase is related to the symptom presentation of severe M1 stenosis.

The computational fluid dynamics methods for the limited flow rate and the small dimensions of an intracranial artery stenosis may help demonstrate the stroke mechanism in intracranial atherosclerosis. We have modeled the high wall shear stress (WSS) in a severe M1 stenosis. The high WSS in the systolic phase of the cardiac cycle was well-correlated with a thick fibrous cap atheroma with enhancement, as was determined using high-resolution plaque imaging techniques in a severe stenosis of the middle cerebral artery.

High flux filtration medium based on nanofibrous substrate with hydrophilic nanocomposite coating.

A novel high flux filtration medium, consisting of a three-tier composite structure, i.e., a nonporous hydrophilic nanocomposite coating top layer, an electrospun nanofibrous substrate midlayer, and a conventional nonwoven microfibrous support, was demonstrated for oil/water emulsion separations for the first time.

Simultaneous determination of amoxicillin and clavulanic acid in human plasma by HPLC-ESI mass spectrometry.

A simple, fast and sensitive high-performance liquid chromatography (HPLC)-mass spectrometric (MS) method has been developed for simultaneous determination of amoxicillin and clavulanic acid in human plasma using terbutaline as internal standard. After precipitation of the plasma proteins with acetonitrile, the analytes were separated on a C(8) reversed-phase column with formic acid-water-acetonirile (2:1000:100) and detected using electrospray ionization (ESI) mass spectrometry in negative selected ion monitoring (SIM) mode. The method was validated and successfully applied to analysis of amoxicillin and clavulanic acid in clinical studies.

DNA capillary electrophoresis using poly(vinyl alcohol). II. Separation media.

We represent the first extensive study on DNA capillary electrophoresis using various poly(vinyl alcohol) (PVAL)-related polymers as separation media. As a separation medium, PVAL homopolymer has shown poor resolutions probably due to its very strong hydrogen-bonding characteristics, resulting in extensive self-aggregation. On the other hand, poly(vinyl alcohol-co-vinyl acetate) and poly(vinyl alcohol-co-1-vinyl-2-pyrrolidone) (PVAL-VP), both with a degree of polymerization of approximately 3.

DNA capillary electrophoresis using poly(vinyl alcohol). I. Inner capillary coating.

Two new methods of inner capillary coating with poly(vinyl alcohol) (PVAL) have been investigated and evaluated by performing DNA capillary electrophoresis (CE) using PVAL as a separation medium and by measuring the electroosmotic flow (EOF) mobility. The treatment of capillaries with a silanol-group modified PVAL (PVAL-Si) has been found to give good coating effects for improving the resolution of DNA CE and for reducing the EOF. This coating must be effectively achieved by combining the adsorptive property of PVAL chains onto silica with the reaction between the silanol groups of PVAL-Si and the silica surface.