Publications by authors named "KyungMok Park"

Green tea extract derived from the leaves of L. (CS), is a representative beverage with antioxidant, anti-cancer, and anti-viral properties. CS extract is also used in cosmetics.

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Morin is a well-known flavonoid, and has been reported to have various properties, such as anti-cell death, antioxidant, and anti-inflammatory properties. Although studies on the biochemical and biological actions of morin have been reported, the melanin biosynthesis effects and molecular mechanisms are unknown. In this study, we first found that morin has the effect of enhancing melanin biosynthesis in B16F10 mouse melanoma cells, and analyzed the molecular mechanism.

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Article Synopsis
  • The study aimed to analyze the metabolic differences in ginseng berries by their cultivation age and ripening stages using gas chromatography-mass spectrometry (GC-MS).
  • Harvesting was done weekly during five ripening stages of ginseng aged three and four years, revealing distinct metabolic changes over time.
  • The analysis showed that three-year-old ginseng had higher levels of certain amino acids while four-year-old berries showed different metabolites, and a random forest machine learning model was effective in predicting age and ripening stage with low error rates.
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Ginseng () has long been used as a traditional medicine for the prevention and treatment of various diseases. Generally, the harvest time and age of ginseng have been regarded as important factors determining the efficacy of ginseng. However, most studies have mainly focused on the root of ginseng, while studies on other parts of ginseng such as its berry have been relatively limited.

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Article Synopsis
  • The study examined the antioxidant and antibacterial properties of leaf extracts using different solvents like hexane, ethyl acetate, and methanol, among others.
  • The methanolic extract had the strongest antioxidant activity, while the ethyl acetate extract was most effective against antibiotic-resistant bacteria, particularly MRSA strains.
  • Six active compounds, including vitamin E, were identified, highlighting the potential of these extracts in treating diseases related to oxidative stress and resistant bacterial infections.*
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Inflammation is a commonly observed immune reaction, and rheumatoid arthritis is a particularly severe inflammatory disease. In this study, we used an air pouch mouse model to evaluate the anti-inflammatory potential of Allium hookeri, which has both been used as a culinary material and a traditional medicine in south-eastern Asia for many years. Allium hookeri suppressed typical symptoms of inflammation, such as condensation of the air pouch membrane, and inhibited the expression of several inducible proinflammatory cytokines such as IL-1β, IL-6, IL-13, and TNF-α.

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Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intake. Although an ingredient may have a history of use as a culinary material, changes in the environment over time suggest that the acceptable maximum intake each of food/culinary material should be regularly evaluated.

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Responding to the need for recombinant acidic fibroblast growth factor in the pharmaceutical and cosmetic industries, we established a scalable expression system for recombinant human aFGF using transient and a DNA replicon vector expression in . Recombinant human-acidic fibroblast growth factor was recovered following infiltration of . The optimal time point at which to harvest recombinant human acidic fibroblast growth factor expressing leaves was found to be 4 days post-infiltration, before necrosis was evident.

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