Publications by authors named "Kyung-Nam Ko"

Cervical cancer is a malignant neoplasm arising from cells that originate in the cervix uteri. It is the second most prevalent cancer among women. It can have several causes; an infection with some type of human papillomavirus (HPV) is the greatest risk factor for cervical cancer.

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Extremely low-frequency electromagnetic fields (ELF-EMF) affect numerous biological functions such as gene expression, cell fate determination and even cell differentiation. To investigate the correlation between ELF-EMF exposure and differentiation, bone marrow derived mesenchymal stem cells (BM-MSCs) were subjected to a 50-Hz electromagnetic field during in vitro expansion. The influence of ELF-EMF on BM-MSCs was analysed by a range of different analytical methods to understand its role in the enhancement of neural differentiation.

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Article Synopsis
  • Diamond Blackfan anemia (DBA) is a rare condition mainly affecting infants and is characterized by reduced red blood cell production; this study reviewed 56 patient records over 20 years to understand national experiences of DBA.
  • The results showed a male preponderance among patients, with early diagnosis (median age 4 months) and a significant percentage (38.2%) presenting with congenital defects; hemoglobin levels and bone marrow activity indicated severe anemia.
  • While most patients initially responded to steroid treatment, nearly half required further treatment; the study emphasizes the need for comprehensive data collection to improve DBA management and understanding.
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