Publications by authors named "Kyue Hee Choi"
Article Synopsis
- The study examined the clinical outcomes of 44 patients with Pleomorphic High-Grade Squamous Intraepithelial Lesions (PHSILs), characterized by abnormal cell nuclei and high mitotic activity.
- Most patients (89.5%) were positive for high-risk HPV, but no single type was dominant; treatment included conization and some required hysterectomy.
- The incidence of concurrent squamous cell carcinoma was low (4.5%) and recurrence was rare (2.3%), suggesting that PHSIL may not need more aggressive treatment than conventional HSIL, although regular follow-ups are essential to monitor for recurrences.
Article Synopsis
- The study focused on diagnosing and classifying IDH-wildtype diffuse astrocytic gliomas to inform treatment and prognosis, especially differentiating glioblastoma (GBM) from lower-grade variants when DNA methylation analysis isn’t possible.
- A total of 479 glioma cases were examined, revealing 91.6% were diagnosed as GBM while 8.4% were classified as lower-grade gliomas not fitting established criteria.
- Findings highlighted that certain genetic alterations, particularly PTEN and EGFR mutations, were prevalent in GBM; however, mTOR pathway mutations correlated with better prognoses despite histological similarities to aggressive tumors.*
Purpose: To elucidate whether a high level of microsatellite instability (MSI-high) in colon cancer influences the CT assessment of regional lymph node (rLN) morphology and diagnostic performance on predicting pathological node-negative (pN0) patients.
Method: We retrospectively reviewed 507 patients with cecal/proximal ascending colon cancer (age, 63.0 ± 11.
Background/aim: Ovarian endometrioid carcinoma (EC) and high-grade serous carcinoma (HGSC) may exhibit various growth patterns and mimic mesonephric-like adenocarcinoma (MLA). We investigated the clinicopathological and molecular features of ovarian carcinomas with mesonephric-like differentiation (MLD).
Patients And Methods: We analyzed the electronic medical records and pathology slides of two EC-MLD and three HGSC-MLD patients, and conducted immunostaining and targeted sequencing of their samples.
Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis.
J Pathol Transl Med
September 2021
Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple masses on the scalp. Excisional biopsy was done and the mass revealed fascicles of smooth muscle fibers which showed positive staining for smooth muscle actin, thus confirming the diagnosis of leiomyosarcoma.
View Article and Find Full Text PDFMisdiagnosis of endocervical adenocarcinoma (EAC) as endometrial endometrioid carcinoma (EEC) is one of the major concerns when evaluating endometrial curettage specimens. It is difficult to differentiate EAC involving the endometrium from EEC, particularly when the specimens have only a few small tumor fragments. We report a case of endocervical adenocarcinoma (AIS) with multifocal microscopic involvement of the endometrium.
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