Publications by authors named "Kyu Yong Ko"
Article Synopsis
- Rheumatic heart disease (RHD) poses significant health risks, particularly in women, but this case examines its effects in a young Asian male with severe symptoms.
- The 46-year-old patient, with a history of mitral valvuloplasty, presented with serious issues like severe mitral stenosis and tricuspid regurgitation, requiring surgical intervention.
- The case illustrates the chronic nature of RHD and stresses the importance of regular follow-ups and a team approach in managing complex heart conditions for better outcomes.
Article Synopsis
- South Korea's economic growth over the past two decades has affected the clinical profile of patients with rheumatic mitral stenosis (MS), leading to older patients with more severe conditions and comorbidities like hypertension and atrial fibrillation.
- Analysis of data from 2,337 patients showed that while the rate of mitral interventions increased, the overall clinical outcomes worsened, indicating a need for improved treatment strategies.
- Despite stable stroke incidence due to better anticoagulation therapy, the findings emphasize the challenges faced as the healthcare landscape transitions with the country’s development.
Article Synopsis
- Percutaneous mitral valvuloplasty (PMV) is an effective treatment for patients with severe rheumatic mitral stenosis (RMS), but the impact of changes in mitral valve area (∆MVA) during the procedure is not well understood.
- A study analyzed 308 patients from the MASTER registry, focusing on those undergoing their first PMV, and found that a ∆MVA greater than 0.5 cm² correlated with better long-term health outcomes.
- The research indicates that not only achieving optimal post-procedure results but also aiming for a significant increase in ∆MVA could improve patient prognosis in PMV surgeries.
Article Synopsis
- * Researchers analyzed data from 359 TAVR patients from 2015 to 2021, matching 120 patients for outcome comparison between ICE with monitored anesthesia care (MAC) and TEE with general anesthesia (GA).
- * Results showed similar rates of the primary outcome (about 18.3% for ICE-MAC and 20.0% for TEE-GA) and other complications like paravalvular regurgitation and bleeding, indicating ICE is a safe
Article Synopsis
- This study compared the effectiveness of percutaneous mitral valvuloplasty (PMV) and mitral valve replacement (MVR) in treating severe mitral stenosis (MS) defined as mitral valve area (MVA) ≤ 1.5 cm, using data from the MASTER registry involving 3140 patients.
- The analysis focused on 442 patients, revealing that while primary outcomes like cardiovascular death and heart failure hospitalization were similar for both treatment options, MVR resulted in fewer secondary outcomes, particularly in very severe MS (VS-MS) cases.
- The study concluded that although neither treatment significantly impacted mortality or hospitalization rates, MVR may be preferred over PMV for VS-MS patients due to a higher need for redo interventions
Article Synopsis
- Aortic valve replacement (AVR) is crucial for treating symptomatic patients with severe aortic stenosis (AS), but there's limited data on early AVR benefits for those with normal-flow, low-gradient (NFLG) AS.
- In a study of 281 symptomatic NFLG AS patients, 121 underwent early AVR while the other 121 received conservative care; results indicated that early AVR significantly reduced the combined risk of death and heart failure (HF) hospitalization.
- The early AVR group experienced lower HF hospitalizations and had promising findings that warrant further investigation in randomized studies to confirm these benefits.
Article Synopsis
- - The study investigated the progression of moderate aortic stenosis (AS) using data from 686 patients and identified two groups based on how their heart condition progressed: slow (44.6%) and rapid (55.4%).
- - The rapid progression group exhibited higher initial systolic mean pressure gradient (MPG) readings and had a significantly greater rate of aortic valve replacement (AVR), while the prevalence of atrial fibrillation was more common in the slow progression group.
- - The findings suggest that a higher initial MPG (≥ 24 mmHg) can predict faster AS progression and increased AVR rates, providing important insights for managing moderate AS in patients.
Background: There are insufficient data regarding the risk factors associated with valve dysfunction of bioprosthetic valves in the mitral position This study aimed to investigate the factors associated with bioprosthetic mitral valve (MV) dysfunction (MVD).
Methods: A total of 245 patients (age 67.2±11.
Introduction: This study aimed to elucidate the relationship between premature ventricular complexes (PVCs) and right ventricular (RV) dysfunction, and the effects of radiofrequency catheter ablation (RFCA) on RV function.
Methods: A total of 110 patients (age, 50.8 ± 14.
Impact of right atrial enlargement on clinical outcome in patients with atrial fibrillation.
Front Cardiovasc Med
September 2022
Background: Left atrial (LA) remodeling is associated with adverse cardiovascular events, including heart failure (HF) and stroke in patients with atrial fibrillation (AF). However, there are limited data on the value of right atrial (RA) remodeling in this population. We investigated the prognostic role of RA enlargement in patients with non-valvular AF.
View Article and Find Full Text PDFInflammatory pseudotumour originating from congenital double atrial septum.
Eur Heart J Cardiovasc Imaging
November 2022
Right ventricular compression by distended stomach: a rare cause of postprandial dyspnoea.
Eur Heart J Cardiovasc Imaging
October 2022
Background Rheumatic mitral stenosis is a significant cause of valvular heart disease. Pulmonary arterial systolic pressure (PASP) reflects the hemodynamic consequences of mitral stenosis and is used to determine treatment strategies. However, PASP progression and expected outcomes based on PASP changes in patients with moderately severe mitral stenosis remain unclear.
View Article and Find Full Text PDFIvabradine is a selective inhibitor of the sinoatrial node "funny" current, prolonging the slow diastolic depolarization. As it has the ability to block the heart rate selectively, it is more effective at a faster heart rate. It is recommended for the treatment of heart failure reduced ejection fraction in the presence of beta-blocker therapy for the further reduction of the heart rate.
View Article and Find Full Text PDFObjectives: We aimed to identify mechanical and pharmacological revascularization strategies correlated with the index of microcirculatory resistance (IMR) in ST-elevation myocardial infarction (STEMI) patients.
Background: Microvascular dysfunction (MVD) after STEMI is correlated with infarct size and poor long-term prognosis, and the IMR is a useful analytical method for the quantitative assessment of MVD. However, therapeutic strategies that can reliably reduce MVD remain uncertain.
Background: Vasovagal syncope (VVS) is a common cause of recurrent syncope. Nevertheless, the exact hemodynamic mechanism has not been elucidated. Pulse wave analysis (PWA) is widely used to evaluate vascular properties, as it reflects the condition of the entire arterial system.
View Article and Find Full Text PDFHypertrophic cardiomyopathy (HCM) is a genetic cardiac disease that represents a broad spectrum of morphologic features and clinical presentations. However, little is known about the impact of gender differences in heart failure (HF) development in non-obstructive HCM. We assessed clinical and echocardiographic parameters according to gender in patients with non-obstructive HCM and evaluated the impact of gender on HF presentation and cardiovascular (CV) outcomes in this population.
View Article and Find Full Text PDFAims: We aimed to investigate whether thrombus aspiration could preserve the index of microcirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI).
Methods And Results: Sixty-three patients with STEMI were randomised into two groups: primary PCI after thrombus aspiration (aspiration group, n=33) and primary PCI without thrombus aspiration (non-aspiration group, n=30). IMR was measured using a pressure-temperature sensor-tipped coronary wire.