Bone density benefits with periodic fluid redistribution during diminished muscular activity in humans.

Objective: Bone loss is an established reaction to diminished muscular activity (Hypokinesia; HK). It has been assumed that periodic fluid redistribution (PFR) could contribute to vascular volume. The fluid volume expansion would then increase tissue perfusion.

Potential benefits of potassium deposition with periodic fluid redistribution using periodic head down tilt during diminished muscular activity.

Objective: Fluid redistribution (FR) is an important cornerstone in treating diseases. Findings of FR with periodic head down tilt (PHDT) had sparked renewed interest in treating electrolyte disturbances. Therefore this study aimed to determine the potential benefits of potassium (K+) deposition with periodic FR by PHDT during diminished muscular activity (hypokinesia; HK).

Potassium deposition during and after hypokinesia in potassium supplemented and unsupplemented rats.

The aim of this study was to determine that hypokinesia (restricted motor activity) could increase potassium (K+) losses with decreased tissue K+ content showing decreased K+ deposition. To this end, measurements were made of K+absorption, tissue K+ content, plasma K+ levels, fecal and urinary K+ excretion during and after hypokinesia (HK) with and without K+ supplementation. Studies conducted on male Wistar rats during a pre-hypokinetic period, a hypokinetic period and a post-hypokinetic period.