Publications by authors named "Kyowon Gu"
Background: This study aimed to assess the significance of elevated carbohydrate antigen (CA) 19-9 in postoperative surveillance of extrahepatic bile duct cancer and to identify short-term recurrence predictors.
Methods: This retrospective study included patients with elevated CA 19-9 post-curative surgery. Patients were categorized into positive and negative CT groups based on the detection of recurrence at CA 19-9 elevation.
Article Synopsis
- The study evaluated whether micro-flow imaging (MFI) is as effective as contrast-enhanced ultrasonography (CEUS) for identifying segmental congestion in patients who had living donor liver transplants.
- Data from 63 patients who underwent the procedure were analyzed, focusing on imaging results and laboratory values to assess congestion, with postoperative CT scans serving as the reference standard.
- Results indicated that MFI had comparable sensitivity (73.9%) and specificity (67.5%) to CEUS (sensitivity 78.3%, specificity 75.0%), suggesting that MFI could be a suitable alternative for detecting postoperative complications.
Objectives: We assessed the value of the diffusion-weighted image (DWI) for predicting intrahepatic biliary complications (IHBC) after ABO-incompatible liver transplantation (ABOi-LT), potentially leading to refractory cholangitis.
Materials And Methods: In this retrospective study at a single center, 56 patients who underwent ABOi-LT from March 2021 to January 2023 were analyzed. All received magnetic resonance cholangiopancreatography (MRCP) and DWI during the postoperative hospitalization.
Local ablation therapy, encompassing radiofrequency ablation (RFA), microwave ablation, and cryoablation, has emerged as a crucial strategy for managing small hepatocellular carcinomas (HCCs), complementing liver resection and transplantation. This review delves into the clinical significance of tumor size, location, and biology in guiding treatment decisions for HCCs undergoing local ablation therapy, with a focus on tumors smaller than 3 cm. Tumor size significantly influences treatment outcomes, with larger tumors associated with poorer local tumor control due to challenges in creating sufficient ablative margins and the likelihood of microvascular invasion and peritumoral satellite nodules.
View Article and Find Full Text PDFObjective: We analyzed the incidence and mortality rate of gastrointestinal (GI) tract perforation after radiofrequency ablation (RFA) for hepatic tumors and assess its risk factors.
Methods: This retrospective cohort study included 4799 patients with malignant tumors who underwent RFA (n = 7206). Sixty-nine cases of thermal injury to the GI tract were identified via a search of the electronic medical record system using index terms and divided into two groups according to the thermal injury with (n = 8) or without (n = 61) GI tract perforation based on follow-up CT reports.
Article Synopsis
- The study assessed how preoperative MRI characteristics influence the outcomes of patients with large single hepatocellular carcinoma (HCC) undergoing surgery.
- It analyzed data from 151 patients, focusing on tumor size, margins, and the degree of hypovascularity during MRI, finding that factors like larger tumor size and greater hypovascularity were linked to worse survival rates.
- The results highlighted the need for careful management in patients with specific MRI findings, indicating that these features could help tailor treatment strategies post-surgery.
Article Synopsis
- The study evaluates how well GPT-4 can extract liver cancer-related information (LI-RADS features) from MRI reports written in both Korean and English.
- Researchers created 160 fake reports and considered both these and genuine reports to test the model's accuracy in extracting the relevant data.
- Results showed high accuracy (up to 99% for some features), but the model still needs improvements for consistency and effectiveness in real-world applications.
Article Synopsis
- Magnetic resonance elastography (MRE) is an effective noninvasive method for diagnosing liver fibrosis and predicting intrahepatic recurrence in patients with hepatocellular carcinoma (HCC) after surgery.
- A study of 80 patients showed that a liver stiffness (LS) measurement of 4.35 kPa or higher indicated a higher likelihood of recurrence, with 16.3% of patients experiencing it over a median follow-up of 32 months.
- The research found that MRE-recurrence and microvascular invasion were significant independent factors affecting recurrence-free survival rates, highlighting the potential of MRE in preoperative assessments.
Objectives: To investigate the hepatobiliary enhancement patterns of gadoxetic acid (Gd-EOB-DTPA) MRI and the temporal evolution of focal nodular hyperplasia (FNH)-like lesions in pediatric cancer survivors.
Methods: We retrospectively included pediatric cancer survivors who had new liver lesions detected during surveillance imaging and who were diagnosed with FNH-like lesions by Gd-EOB-DTPA MRI without the aid of a hepatobiliary phase. The hepatobiliary enhancement patterns of FNH-like lesions were categorized as homogeneous hyperintense/isointense, heterogeneous hyperintense, and ring-like enhancement.
Objective: Little is known about prognostic factors for lung squamous cell carcinoma (SCC). We aimed to explore radiologic and clinical factors affecting prognosis and to compare the prognosis of both central and peripheral lung SCCs.
Materials And Methods: Radiologic, clinical, and pathologic profiles of surgically confirmed SCCs from 382 patients were retrospectively reviewed.
Objectives: To investigate the value of blood oxygenation level-dependent (BOLD) MRI as a predictor of clinical outcomes in cervical cancer patients treated with concurrent chemoradiotherapy (CCRT).
Method: Enrolled 92 patients with stage IB2-IVB cervical cancer who received CCRT underwent 3-T BOLD MRI before treatment. The R2* value (rate of spin dephasing, s) was measured in the tumor.
Objectives: To investigate the prognostic value of diffusion-weighted imaging (DWI) in predicting clinical outcome in patients with cervical cancer after concurrent chemoradiotherapy (CCRT).
Methods: We enrolled 124 cervical cancer patients who received definitive CCRT and underwent 3 T-MRI before and 1 month after initiating treatment. The mean apparent diffusion coefficient (ADC) value was measured on the tumor and the changes in ADC percentage (ΔADC) between the two time points were calculated.
Purpose: To determine the imaging features of hepatic sarcomatous carcinoma including sarcomatous intrahepatic cholangiocarcinoma (S-ICC) and sarcomatous hepatocellular carcinoma (S-HCC) on computed tomography (CT) and gadoxetic acid-enhanced magnetic resonance imaging (MRI).
Materials And Methods: Twenty-four patients with pathologically confirmed S-ICCs (n = 13), S-HCCs (n = 7), sarcomatous carcinoma (n = 2), carcinosarcoma (n = 1), and sarcomatous combined HCC-CC (n = 1) (size range 2.1-23 cm, mean 8.
Objective: The purpose of this study was to demonstrate the usefulness of digital subtraction cystography to identify communicating holes between a spinal extradural arachnoid cyst (SEAC) and the subarachnoid space prior to cyst removal and hole closure.
Materials And Methods: Six patients with SEAC were enrolled in this retrospective study. Digital subtraction cystography and subsequent CT myelography were performed for every patient.