Publications by authors named "Kyoung-Mok Kim"
A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
Jai-Hee Moon Jae-Sik Shin Seung-Woo Hong Soo-A Jung Ih-Yeon Hwang Jeong Hee Kim Jin-Sun Kim Kyoung-Mok Kim Daejin Kim Yeong Seok Kim Jeong Eun Kim Kyu-Pyo Kim Tae Won Kim
Oncotarget
September 2015
Inhibitor of apoptosis proteins (IAPs) plays an important role in controlling cancer cell survival. IAPs have therefore attracted considerable attention as potential targets in anticancer therapy. In this study, we investigated the anti-tumor effect of AZD5582, a novel small-molecule IAP inhibitor, in human pancreatic cancer cells.
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