Publications by authors named "Kyoung Nam Kim"

Background: Previous studies on the associations of per- and polyfluoroalkyl substances (PFASs) and heavy metals with lipid profiles among adolescents have been scarce. We sought to investigate the associations of PFASs and heavy metals with blood lipid levels in a representative sample of Korean adolescents.

Methods: Data from the Korean National Environmental Health Survey (2018-2020) were used.

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This simulation-based study presented a novel hybrid RF antenna array designed for neck cancer treatment within a 7T MRI system. The proposed design aimed to provide microwave hyperthermia to release 19F-labeled anticancer drugs from thermosensitive liposomes, facilitating drug concentration monitoring through 19F imaging and enabling 1H anatomical imaging and MR thermometry for temperature control. The design featured a bidirectional microstrip for generating the magnetic |B1|-fields required for 1H and 19F MR imaging, along with a patch antenna for localized RF heating.

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Background: Although the association between low ambient temperature and cardiovascular disease (CVD) is well-established, the effect of winter energy prices on this association remains unknown.

Aim: This ecological study aimed to investigate whether changes in natural gas prices (NGP), which account for a significant portion of winter energy prices in Korea, affect the association of cold spells with hospital admissions and mortality due to CVD.

Methods: Data from the National Health Insurance Service and Statistics Korea were used to determine the daily number of hospital admissions and mortality rates associated with CVD.

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Article Synopsis
  • The study investigates how exposure to endocrine-disrupting chemicals (EDCs) during pregnancy and childhood affects early breast development (thelarche) in girls, specifically before age 8.
  • Researchers analyzed data from 211 girls, focusing on chemicals like cadmium, lead, mercury, bisphenol-A (BPA), and others from prenatal samples and assessed breast development through Tanner staging.
  • Results revealed that higher prenatal exposure to cadmium increased the likelihood of early thelarche, while prenatal exposure to BPA appeared to lower this risk; however, no significant associations were found with chemical exposures at age 8.
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Background: Disruption of thyroid function can profoundly affect various organ systems. However, studies on the association between air pollution and thyroid function are relatively scarce and most studies have focused on the long-term effects of air pollution among pregnant women.

Objectives: This study aimed to explore the associations between short-term exposure to air pollution and thyroid function in the general population.

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Background: A poor diet is a risk factor for chronic obstructive pulmonary disease (COPD). The interaction between dietary factors and cigarette smoking in the development of COPD is unclear. We investigated the interactions between dietary patterns and smoking status on COPD-related outcomes.

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It has often been reported that thyroid-specific autoimmune diseases (ADs), such as Hashimoto's thyroiditis and Graves' disease, could increase the risk of thyroid cancer, but the association between other ADs beyond thyroid and thyroid cancer has not been well investigated. This study aimed to examine the risk of thyroid cancer in patients with eight ADs compared with those without ADs. This nationwide retrospective matched cohort study was conducted to investigate the relationship of eight ADs (Hashimoto's thyroiditis, Graves' disease, type 1 diabetes mellitus, Sjogren's disease, inflammatory bowel disease [IBD], vitiligo, systemic lupus erythematosus, and rheumatoid arthritis [RA]) with the risk of incident thyroid cancer using the National Health Insurance Service-National Sample Cohort.

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Objectives: Young children's feeding characteristics can play an important role in eating habits and health during later childhood. This study was conducted to examine the associations of feeding characteristics with dietary patterns and obesity in children.

Methods: This study utilized data from the Korea National Health and Nutrition Examination Survey conducted between 2013 and 2017.

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Background: The potential differences by sex in the association between body mass index (BMI) and thyroid cancer risk remain unconfirmed.

Methods: Data from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS; 2002-2015; population size = 510,619) and the Korean Multi-center Cancer Cohort (KMCC) data (1993-2015; population size = 19,026) were used. We constructed Cox regression models, adjusted for potential confounders, to evaluate the association between BMI and thyroid cancer incidence in each cohort, and assessed the consistency of the results.

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Electrical property tomography (EPT) is a noninvasive method that uses magnetic resonance imaging (MRI) to estimate the conductivity and permittivity of tissues, and hence, can be used as a biomarker. One branch of EPT is based on the correlation of water and relaxation time T1 with the conductivity and permittivity of tissues. This correlation was applied to a curve-fitting function to estimate electrical properties, it was found to have a high correlation between permittivity and T1 however the computation of conductivity based on T1 requires to estimate the water content.

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Background: Previous epidemiological studies have suggested that phthalate exposure may contribute to neurocognitive and neurobehavioral disorders and decreased muscle strength and bone mass, all of which may be associated with reduced physical performance. Walking speed is a reliable assessment tool for measuring physical performance in adults age 60 y and older.

Objective: We investigated associations between urinary phthalate metabolites and slowness of walking speed in community-dwelling adults ages 60-98 y.

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Background/objectives: Previous studies have shown an association between breastfeeding and higher fruit and vegetable consumption and the level of dietary variety in children. However, few studies have reported this association on the feeding characteristics. Therefore, this study examined the association of the feeding characteristics with the consumption of fruit and vegetable and dietary variety in children.

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Background: Studies on the modifying effects of dietary factors on the association between air pollution and diabetes-related outcomes are limited. We examined whether dietary nutrients could modify the association between long-term air pollution exposure and the development of diabetes.

Methods: We used data from the Cardiovascular Disease Association Study, which enrolled adults aged 40-69 years in Korea between 2005 and 2011 and followed them up until 2016 (n = 14,667).

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Evidence supporting the effect of individual protective measures (IPMs) on air pollution is relatively scarce. In this study, we performed a systematic review and meta-analysis to investigate the effects of air purifiers, air-purifying respirators, and cookstove changes on cardiopulmonary health outcomes. We searched PubMed, Scopus, and Web of Science until December 31, 2022, 90 articles and 39,760 participants were included.

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Background: Emerging evidence supports an association between heat exposure and acute kidney injury (AKI). However, there is a paucity of studies on the association between cold exposure and AKI.

Objective: We aimed to investigate the associations of cold exposure with hospital admission and mortality due to AKI and to explore whether these associations were influenced by age and sex.

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In this paper, we present a study on the effects of varying the position of a single tuning capacitor in a circular loop coil as a mechanism to control and produce non-symmetric current distribution, such that could be used for magnetic resonance imaging (MRI) operating at ultra-high frequency (UHF). This study aims to demonstrate that the position of the tuning capacitor of a circular loop could improve the coupling between adjacent coils, used to optimize transmission field uniformity or intensity, improve signal-to-noise ratio (SNR) or specific absorption rate (SAR). A typical loop coil used in MRI consists of symmetrically distributed capacitors along the coil; this design is able to produce uniform current distributions inside the coil.

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Objectives: This study explored the effects of short-term exposure to air pollution on hospital admissions for autism spectrum disorder (ASD), a proxy for symptom aggravation, among Korean children aged 5-14 years.

Design: Time-series study.

Setting, Participants And Outcome Measures: We used data from the National Health Insurance Service (2011-2015).

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Dielectric relaxation theory describes the complex permittivity of a material in an alternating field; in particular, Debye theory relates the time it takes for an applied field to achieve the maximum polarization and the electrical properties of the material. Although, Debye's equations were proposed for electrical polarization, in this study, we investigate the correlation between the magnetic longitudinal relaxation time T1 and the complex electrical permittivity of tissue-mimicking phantoms using a 7 T magnetic resonance scanner. We created phantoms that mimicked several human tissues with specific electrical properties.

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Article Synopsis
  • The paper outlines a collaboration with Seoul's health department during the COVID-19 pandemic, focusing on short-term forecasting of new confirmed and severe cases.
  • It examines the impact of external infections versus internal transmission to inform government policies on interventions.
  • The study emphasizes predicting weekly confirmed cases by district using multivariate time series models and an ensemble method for better accuracy in resource allocation.
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This study aimed to investigate the association between blood glucose control and subjective cognitive decline in adult patients with diabetes. Using the 2018 data from the community health survey, we included 18,789 patients with diabetes aged ≥50 years who had complete responses recorded. Blood glucose control was the independent variable, and subjective cognitive decline was the dependent variable.

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Background: Climate change is predicted to increase the frequency, intensity, and duration of extreme cold events in the mid-latitudes. However, although diabetes is one of the most critical metabolic diseases due to its high and increasing prevalence worldwide, few studies have investigated the short-term association between cold exposure and diabetes-related outcomes.

Objective: The aim of this study was to investigate the associations between cold spells and their characteristics (intensity, duration, and seasonal timing) and hospital admission and mortality due to diabetes.

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Background: There is insufficient evidence of an association between long-term exposure to air pollution and changes in blood lipid levels, and assessments may be influenced by residual confounding factors, such as socioeconomic status.

Objectives: To investigate the associations between long-term exposure to air pollution and blood lipid profiles while controlling for the risk of residual confounding factors.

Methods: We conducted a study involving conscripted Korean soldiers to assess the associations between air pollution and blood lipid levels.

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Objectives: The aim of this study was to estimate the age-specific effects of 8-hour maximum ozone levels on pneumonia in children and adolescents.

Methods: We performed quasi-Poisson regression analyses for individuals of 0-4 years, 5-9 years, 10-14 years, and 15-19 years of age using nationwide time-series data from the Korea (2011-2015). We constructed distributed lag linear models employing a generalized difference-in-differences method and controlling for other air pollutants.

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Background: The aim of this study was to estimate the 8-year prevalence and mortality statistics of autism spectrum disorder (ASD) according to birth year (2002-2012).

Methods: We used the National Health Insurance Service database with 4,989,351 children born from 2002 to 2012 including 35,529 children diagnosed with ASD until 8 years of age. The 8-year cumulative prevalence of ASD was calculated annually (2010-2020) with 8 years of follow-up.

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Article Synopsis
  • The study analyzed 353 mother-child pairs, finding significant associations between air pollutant exposure during the first trimester of pregnancy and behavioral problems in children at age five, as assessed by the Child Behavior Checklist.
  • Results indicated that exposure during critical early life stages correlated with increased behavioral issues, notably more pronounced in boys, highlighting the need for better air quality control to protect vulnerable populations like pregnant women and young children.
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