Publications by authors named "Kyou Chae Lee"

Facial skin quality profoundly influences an individual's perceived appearance and is an important aspect of facial rejuvenation. Facial pore enlargement is one of the most common concerns among Asian individuals that adversely impacts perceived skin surface evenness and affects overall skin quality. One of the major causes of enlarged pores is facial skin laxity.

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Background: Various systemic agents have been assessed for the treatment of alopecia areata (AA); however, there is a paucity of comparative studies.

Objective: To assess and compare cyclosporine and betamethasone minipulse therapy as treatments for AA with regard to effectiveness and safety.

Methods: Data were collected from 88 patients who received at least 3 months of oral cyclosporine (n=51) or betamethasone minipulse therapy (n=37) for AA.

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Background: Laser/light-based devices may provide an alternative to conventional acne therapeutics in some patients with nonresponsive acne.

Objective: We investigated the efficacy of red or infrared light-emitting diode (LED) devices in a mouse model of Propionibacterium acnes-induced inflammation through clinical examination and histopathological and immunohistochemical studies.

Methods: A human-derived Propionibacterium acnes suspension (10(9) colony-forming units /µl) was injected into the back of an HR-1 mouse.

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Background: There is no appropriate in vivo animal model that reflects the inflammatory response of human acne.

Objective: This study investigated the effect of Propionibacterium acnes on the development of inflammatory acne-like lesions in four mouse strains with different degrees of immune response for the development of an optimal mouse model of inflammatory acne.

Methods: Human P.

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