Publications by authors named "Kyosuke Murata"
Article Synopsis
- - Pulmonary fibrosis (PF) has a high mortality rate, making the search for effective prevention and treatment strategies crucial; one promising approach involves the use of (-)-Epigallocatechin-3-gallate (EGCG), a compound found in green tea that shows antifibrotic properties.
- - A study examined how EGCG influences microRNAs (miRNAs) found in extracellular vesicles from human umbilical vein endothelial cells (HUVECs) and identified 31 miRNAs that were affected by EGCG, with 27 being increased and 4 decreased.
- - Notably, miR-6757-3p was found to potentially target the TGF-β receptor 1 (TGF
Scope: Procyanidin C1 (PC1) is an epicatechin trimer found mainly in grapes that is reported to provide several health benefits. However, little is known about the molecular mechanisms underlying these benefits. The aim of this study is to demonstrate the molecular mechanisms by which PC1 operates.
View Article and Find Full Text PDFGreen tea and its major polyphenol epigallocatechin-3-O-gallate (EGCG) have suppressive effect on dietary obesity. However, it remains unsolved what type of diet on which they exhibit high or low anti-obesity effect. In the present study, we investigated whether anti-obesity effect of green tea differs depending on composition of fats or fatty acids that consist high-fat (HF) diet in mouse model.
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