Rev Hosp Clin Fac Med Sao Paulo
October 2004
Purpose: To test an experimental model of chemical mammary carcinogenesis induction in rats.
Methods: Twenty young virgin Sprague-Dawley female rats, aged 47 days, received 20 mg of 7,12-dimethylbenz(a)anthracene (DMBA) intragastrically by gavage. Afterwards, at 8 and 13 weeks, their mammary glands were examined.