Publications by authors named "Kyohei Kawakami"
Jpn J Clin Oncol
November 2024
Article Synopsis
- Methadone has been used in Japan since 2013 for treating severe cancer pain in patients on high doses of opioids, and this study focuses on its effectiveness as a low-dose add-on therapy (5 or 10 mg/day) in over a hundred cases.
- The analysis involved 102 patients, primarily male, averaging 62.8 years old, with most suffering from spinal or pelvic metastases, and pain often stemming from a mix of somatic and neuropathic sources.
- The introduction of low-dose methadone resulted in a significant reduction in the number of rescue doses needed for pain management, indicating its potential effectiveness, though some side effects were noted.
