Publications by authors named "Kyohei Haruta"

Background: People living with human immunodeficiency virus (PLWH) require high rates of medication adherence to antiretroviral therapy (ART) for a successful treatment outcome. Understanding the factors associated with incomplete adherence among those receiving integrase strand transfer inhibitor-containing single-tablet regimens (INSTI-STRs) is crucial for improving treatment outcomes. This study aimed to identify the factors contributing to incomplete ART adherence among Japanese PLWH receiving INSTI-STRs.

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Background: Current antiretroviral therapy (ART) regimens are highly effective; therefore, to differentiate between various regimens, considering patient-reported outcomes is essential. This study aimed to assess patient satisfaction with their current ART regimens and investigate factors associated with the Human Immunodeficiency Virus Treatment Satisfaction Questionnaire: Status (HIVTSQs) score.

Methods: This cross-sectional, multicenter study was conducted in Japan between April and December 2021.

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Article Synopsis
  • Long-acting injectable formulations for HIV treatment have been approved in Japan, though they are not yet first-line options according to current guidelines.
  • A survey of 667 people living with HIV revealed that patient satisfaction was highest with co-payment costs but lowest with daily oral therapy, indicating discomfort with taking pills every day.
  • Factors influencing the preference for long-acting injectables included the size of the tablets and the burden of daily therapy, suggesting that more patients may favor this option if these issues are addressed.
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