Publications by authors named "Kyna Vuong"
Fusion-positive rhabdomyosarcoma (FP-RMS) driven by the expression of the PAX3-FOXO1 (P3F) fusion oncoprotein is an aggressive subtype of pediatric rhabdomyosarcoma. FP-RMS histologically resembles developing muscle yet occurs throughout the body in areas devoid of skeletal muscle highlighting that FP-RMS is not derived from an exclusively myogenic cell of origin. Here we demonstrate that P3F reprograms mouse and human endothelial progenitors to FP-RMS.
View Article and Find Full Text PDFArticle Synopsis
- - Supratentorial hemangioblastomas are rare, benign tumors primarily found in the brain and spine, with more occurrences in women and an average diagnosis age of 44.48 years.
- - A systematic review of 92 articles revealed that these tumors were most frequently located in the sellar/parasellar region, with the solid morphological type being predominant.
- - Complete surgical resection is the preferred treatment, showing favorable outcomes for over 75% of patients, but research on these tumors remains limited due to their rarity.