Assessing site performance in the Altair study, a multinational clinical trial.

Background: Reviewing clinical trial site performance identifies strategies to control outcomes. Performance across 5 geographical regions (36 sites across Asia, Australia, Europe, North America and Latin America) was investigated in a study that randomised 322 HIV-infected individuals.

Methods: Regional performance was compared using descriptive analysis for time to site opening, recruitment, quality of data and laboratory samples.