The effects of fingerprinting agents on the stable isotope ratios of polyethylene films.

Traditional forensic chemical comparisons of polymeric materials are often affected by fingerprinting agents that enhance and visualise finger-marks. This can inhibit detailed analysis used to provide an association or discrimination between two samples. In this study, we have demonstrated that the method for polymer comparisons using isotope ratio mass spectrometry analysis is not affected by fingerprinting matter on the surface in contrast to other forensic instrumental tests.

Intrauterine growth-restricted pregnant rats, from placental ischemic dams, display preeclamptic-like symptoms: A new rat model of preeclampsia.

Preeclampsia (PE) is characterized by de novo hypertension (HTN) and is often associated with intrauterine growth restriction (IUGR). Hallmarks of PE are placental ischemia, decreased nitric oxide (NO) bioavailability, oxidative stress (OS), and organ damage in the kidneys and brain. This study aims to characterize a new model of PE using pregnant IUGR rats from hypertensive placental ischemic dams.

Operational relevance of the Sydney Declaration: The example of the Australian Federal Police (AFP) Forensics Command.

In 2022, a group of eminent forensic scientists published The Sydney Declaration - Revisiting the essence of forensic science through its fundamental principles in Forensic Science International. The Sydney Declaration was delivered to revisit "the essence of forensic science, its purpose, and fundamental principles". At its heart, revisiting these foundational principles is hoped to "benefit forensic science as a whole to be more relevant, effective and reliable".

Macro- and Micro-Structural Alterations in the Midbrain in Early Psychosis.

Introduction: Early psychosis (EP) is a critical period in the course of psychotic disorders during which the brain is thought to undergo rapid and significant functional and structural changes . Growing evidence suggests that the advent of psychotic disorders is early alterations in the brain's functional connectivity and structure, leading to aberrant neural network organization. The Human Connectome Project (HCP) is a global effort to map the human brain's connectivity in healthy and disease populations; within HCP, there is a specific dataset that focuses on the EP subjects (i.

Background survey of polyethylene in the Australian Capital Territory - A demonstration of variability in isotopic abundance values and their application to forensic casework.

Plastics including adhesive tapes, cable ties, and packaging are common evidence types encountered in forensic investigations and casework. Traditional examination techniques such as Fourier Transform Infrared (FTIR) spectroscopy lack specificity and are unable to discern differences within the same polymer structures leaving the analyst with a generic identification. High quality manufacturing methods further amplify the limitations in detecting variability between samples.

Dataset of coded handwriting features for use in statistical modelling.

The data presented here is related to the article titled, "Using handwriting to infer a writer's country of origin for forensic intelligence purposes" (Agius et al., 2017) [1]. This article reports original writer, spatial and construction characteristic data for thirty-seven English Australian writers and thirty-seven Vietnamese writers.

Using handwriting to infer a writer's country of origin for forensic intelligence purposes.

Forensic science has traditionally focused the majority of its resources and objectives towards addressing Court-related questions. However, this view restricts the contribution of forensic science to one process and results in a loss of information as the investigative and intelligence roles are largely neglected. A forensic science discipline suffering from this imbalance is handwriting examination, which may be characterised as a time consuming and subjective process that is mostly carried out towards the end of the investigation for the purpose of judicial proceedings.

The use of handwriting examinations beyond the traditional court purpose.

Traditionally, forensic science has predominantly focused its resources and objectives on addressing court related questions. However, this view restricts the contribution of forensic science to one function and results in lost opportunities as investigative and intelligence roles are often overlooked. A change of perspective and expansion of the contributions of forensic science is required to take advantage of the benefits of abductive and inductive thought processes throughout the investigative and intelligence functions.

The forensic analysis of office paper using oxygen Isotope Ratio Mass Spectrometry, part 2: Characterising the source materials and the effect of production and usage on the δO values of cellulose and paper.

For casework applications, understanding the source processes used to create a material and the effects of those sources on the results obtained by Isotope Ratio Mass Spectrometry (IRMS) of a bulk material is important. Likewise, understanding the effect of environment, home/office printing processes and some forensic testing in at least a basic context, ensures that in casework, enough information on the effects of these variables is available during comparison and interpretation. In this study, which focuses on oxygen isotopic abundance measurements, both fractionation and mixing effects were observed within the pulping and production process.

The forensic analysis of office paper using oxygen isotope ratio mass spectrometry. Part 1: Understanding the background population and homogeneity of paper for the comparison and discrimination of samples.

Isotope ratio mass spectrometry (IRMS) using carbon isotopes has previously been shown to be a robust and discriminating technique for the comparison of document papers. This study aims to examine the inter and intra sample variability for oxygen isotopes measured in standard 80gsm white document papers, to inform the comparison of document papers in forensic casework. 123 paper samples collected from Australia and New Zealand over a 24-month period were measured for their bulk oxygen isotopic abundance and were found to sit within a range of 15‰.

The forensic analysis of office paper using carbon isotope ratio mass spectrometry. Part 3: Characterizing the source materials and the effect of production and usage on the δ13C values of paper.

When undertaking any study of the isotope abundance values of a bulk material, consideration should be given to the source materials and how they are combined to reach the final product being measured. While it is demonstrative to measure and record the values of clean papers, such as the results published as part one of this series, the majority of forensic casework samples would have undergone some form of writing or printing process prior to examination. Understanding the effects of these processes on the δ(13)C values of paper is essential for interpretation and comparison with clean samples, for example in cases where printed documents need to be compared to paper from an unprinted suspect ream.

Bacteraemia in ventricular assist devices: a common complication that need not affect clinical outcomes.

Background: Ventricular assist device (VAD) implantation has become an effective option for patients with severe heart failure. However, device-related infections remain a significant problem. The aim of this study was to describe the incidence and microbiological aetiology of bacteraemia in patients with VADs, and to assess the impact of bacteraemia on clinical outcomes.

The forensic analysis of office paper using carbon isotope ratio mass spectrometry--part 2: method development, validation and sample handling.

This paper describes the development and validation of a method for the analysis of office papers by measuring carbon isotopes using isotope ratio mass spectrometry (IRMS). The method development phase included testing protocols for storage, sample materials, set-up of the analytical run; and examining the effects of other paper examination procedures on IRMS results. A method validation was performed so that the Delta(plus) XP IRMS instrument (Thermo Finnigan, Bremen, Germany) with Flash EA™ 1112 could be used to measure document paper samples for forensic casework.

The forensic analysis of office paper using carbon isotope ratio mass spectrometry--part 1: understanding the background population and homogeneity of paper for the comparison and discrimination of samples.

Isotope Ratio Mass Spectrometry (IRMS) has been shown to be a useful tool in the comparison of materials that are chemically identical either through man-made production processes or for materials that have been naturally produced. Paper therefore, is an ideal material for this type of measurement given that it is manufactured from a naturally produced product that can be difficult to discriminate based on physical feature comparison alone. To determine whether carbon isotopes are useful for discriminating document papers, 125 samples from Australia and New Zealand were collected over a 24-month period.

Pediatric experience with the VentrAssist LVAD.

Purpose: The purpose of this study is to describe the first experience of implanting a new left ventricular assist device in pediatric patients with end-stage heart failure.

Description: In two recent prospective, international, multicenter clinical trials, three children (aged
Evaluation: Despite the patients' disease severity (each child was in extremis at the time of implantation), VentrAssist (Ventracor Limited) implantation enabled each patient to be discharged home from the hospital.