Do adiponectin, TNFalpha, leptin and CRP relate to insulin resistance in pregnancy? Studies in women with and without gestational diabetes, during and after pregnancy.

Background: The role of adiponectin, tumour necrosis factor alpha (TNFalpha), leptin and C-reactive protein in the insulin resistance of pregnancy is not clear. We measured their levels in women with gestational diabetes (GDM) and in controls, during and after pregnancy, and related them to insulin secretion and action.

Methods: Nineteen women with GDM and 19 BMI-matched healthy pregnant women underwent intravenous glucose tolerance tests in the third trimester of pregnancy and 4 months postpartum to determine insulin sensitivity (SI) and insulin secretion.

Gestational diabetes in Victoria in 1996: incidence, risk factors and outcomes.

Objectives: To describe the epidemiology of gestational diabetes mellitus (GDM) in Victoria.

Study Design: Population study of all women having singleton births in Victoria in 1996.

Methods: Probabilistic record linkage of routinely collected data and capture-recapture techniques to provide an estimate of the incidence of GDM.