Publications by authors named "Kyle Kramer"
A mixed phenotype is characteristic of de novo Mixed Phenotype Acute Leukemia (MPAL) but can also be seen in other leukemias. It poses substantial classification and management dilemmas. Herein, we report a large cohort of acute leukemia with a mixed phenotype and define Acute Myeloid Leukemia with Mixed Phenotype (AML-MP) and MPAL as two distinct groups by characterizing the clinical, genetic, and transcriptomic features.
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- Regular physical activity is essential for overall health, but understanding how endurance exercise affects molecular signaling is still a work in progress.
- The MoTrPAC project aims to explore these molecular responses by conducting structured endurance training on Fischer 344 rats of different ages and sexes, analyzing various tissues and other biological samples.
- The study found significant improvements in muscle function and fitness markers within just a few weeks of exercise, highlighting age- and sex-related differences and providing valuable resources for future research on exercise responses.
The approved Pfizer and Moderna mRNA vaccines are well known to induce serum antibody responses to the SARS-CoV-2 Spike (S)-protein. However, their abilities to elicit mucosal immune responses have not been reported. Saliva antibodies represent mucosal responses that may be relevant to how mRNA vaccines prevent oral and nasal SARS-CoV-2 transmission.
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