Publications by authors named "Kyle Kalchthaler"
Article Synopsis
- The study aimed to automate the filling of case report forms (CRFs) for a COVID-19 trial across multiple locations in the U.S.
- It utilized data from 27 hospitals and electronic health records to efficiently populate trial forms, successfully processing 499 out of 526 variables for 417 enrolled patients.
- The researchers concluded that the automated system was effective and suggested improvements for future clinical trials.
Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited.
Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19.
Design, Setting, And Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin.
Article Synopsis
- The paper outlines the creation of four affordable biomedical devices (blood pressure monitor, thermometer, weighing scale, and spirometer) specifically designed for the East African context, focusing on a mass-production price of $10 and durability in harsh conditions.
- The blood pressure monitor, thermometer, and weighing scale showed a 6% error margin compared to commercial devices and performed well in field tests in Kenya, while suggesting the spirometer requires redesign for better usability.
- The article emphasizes the potential for developing effective biomedical devices in resource-limited settings, proposing further improvements for easier manufacturing, standardized materials, field calibration, and enhanced user software.