Cellular blue nevus of the uterus: a case report and review of the literature.

Cellular blue nevus is extremely rare in the gynecologic tract with only 2 cases reported thus far, one in the myometrium and the other in the cervix/vagina/hymenal ring. In this report, we present the clinicopathologic features of the second case of cellular blue nevus arising in the myometrium. The patient was a 48-year-old woman who underwent a hysterectomy with bilateral salpingo-oophorectomy for uterine leiomyomas.

Alcohol exposure on postnatal day 5 induces Purkinje cell loss and evidence of Purkinje cell degradation in lobule I of rat cerebellum.

The reduction in neuron number in specific brain regions is one of the most destructive aspects of alcohol-induced developmental brain injury, and its occurrence depends on the timing, pattern, and dose of maternal alcohol consumption during pregnancy. The purpose of this investigation was to quantify the dose-response aspect of Purkinje cell loss and rapid cellular degradation indicative of Purkinje cell loss following a single alcohol exposure on postnatal day 5 in lobule I, a lobule that has been shown to be vulnerable to alcohol-induced injury during cerebellar development. Fluoro-Jade B was used to identify Purkinje cell degeneration in 2-h intervals during the first 24h following the single alcohol exposure.