Macular pigment optical density and visual quality of life.

Purpose: There is robust evidence that higher macular pigment concentrations help reduce both veiling and discomfort glare in patients with or without ocular disease. We investigated whether there was also a relationship between macular pigment optical density (MPOD) and patient surveys about glare or ocular discomfort.

Methods: We measured MPOD psychophysically in 23 healthy subjects and administered the National Eye Institute Visual Functioning Questionnaire (VFQ-25).

Effects of Oral Antihistamines on Tear Volume, Tear Stability, and Intraocular Pressure.

The goal of this study was to investigate the effects of two commonly used oral antihistamines-diphenhydramine and loratadine-on tear volume, tear breakup time, and intraocular pressure. Placebo, diphenhydramine, and loratadine were administered for one week to 33 subjects experimentally blind to the treatment given. All the subjects received all three treatments over a period of six weeks.