Publications by authors named "Kyle A Salem"
We systematically evaluated a variety of MR spiral imaging acquisition and reconstruction schemes using a computational perceptual difference model (PDM) that models the ability of humans to perceive a visual difference between a degraded "fast" MRI image with subsampling of k-space and a "gold standard" image mimicking full acquisition. Human subject experiments performed using a modified double-stimulus continuous-quality scale (DSCQS) correlated well with PDM, over a variety of images. In a smaller set of conditions, PDM scores agreed very well with human detectability measurements of image quality.
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- The study aims to speed up the two-point Dixon fat suppression technique by combining in-phase and out-of-phase k-space data and optimizing keyhole size using a perceptual difference model.
- Keyhole Dixon images were created by adjusting the number of lines in the keyhole data set, incorporating off-resonance correction, and validating the perceptual difference model with human observer experiments to determine the minimal keyhole width needed for equivalent image quality.
- Results showed that using 96 of 192 k-space lines for Water + Fat and full lines for Water - Fat produced images that were perceptually similar to the full two-point Dixon method, achieving a 25% scan time reduction in phantom studies and up to 38% in clinical images, enhancing efficiency
Recent advances in drug delivery techniques have necessitated the development of tools for in vivo monitoring of drug distributions. Gamma emission imaging and magnetic resonance imaging suffer from problems of resolution and sensitivity, respectively. We propose that the combination of X-ray CT imaging and image analysis techniques provides an excellent method for the evaluation of the transport of platinum-containing drugs from a localized, controlled release source.
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