Protective Effect of Alpha 1-Antitrypsin on Renal Ischemia-Reperfusion Injury.

Background: α-Antitrypsin (AAT) is an important protein in the anti-inflammatory response that functions to regulate the activity of serine proteinases. We aimed to evaluate the protective effect of AAT on ischemia-reperfusion injury (IRI) in a mouse model.

Methods: We investigated the effects of AAT in a C57BL/6 mouse model of IRI by dividing them into 4 groups: normal control, sham operated, ischemia-reperfusion (IR), and IR after AAT pretreatment (IR-AAT).

Severe Respiratory Syncytial Virus Pneumonia in a Kidney Transplant Recipient With Desensitization: Case Report and Comprehensive Review of the Literature.

Herein, we report a rare case of severe respiratory syncytial virus pneumonia after kidney transplant in a 46-year-old woman. The patient was diagnosed with end-stage renal disease and underwent living-donor kidney transplant. Direct flow cytometry crossmatch testing yielded positive results, and desensitization treatment with rituximab, plasmapheresis, and im-munoglobulin was performed before transplant.

Erratum: Anti-phospholipase A2 receptor antibody as a prognostic marker in patients with primary membranous nephropathy [Volume 37, Issue 3, September 2018, Pages 248-256].

[This corrects the article on p. 248 in vol. 37, PMID: 30254849.

Anti-phospholipase A2 receptor antibody as a prognostic marker in patients with primary membranous nephropathy.

Background: Phospholipase A2 receptor (PLA2R) has been identified as a major autoantigen in primary membranous nephropathy (MN). We evaluated the association between anti-PLA2R antibodies and clinical outcome in Korean patients with primary MN.

Methods: A total of 66 patients with biopsy-proven MN were included.