Life-threatening gastrointestinal haemorrhage requiring surgical resection caused by SARS-CoV-2 induced ANCA associated vasculitis: A case report.

Introduction And Importance: SARS-CoV-2 infection has been linked to the diagnosis of various autoimmune conditions as well as flares in pre-existing disease. With such high prevalence of SARS-CoV-2 in the community, it is important to consider rare manifestations of autoimmune conditions when patients present with severe symptoms. Multi-specialty care is required to ensure optimal outcomes and prompt diagnosis.

Penile Epithelioid Angiomatoid Nodule.

Cutaneous epithelioid angiomatoid nodule is a rare clinical entity that is common on the trunk and limbs. This is the first report of penile cutaneous epithelioid angiomatoid nodule. Although it is a benign entity, it must be differentiated from vascular neoplasms, as it can bear similar clinical and pathologic features.

Detection of MYC rearrangement in high grade B cell lymphomas: correlation of MYC immunohistochemistry and FISH analysis.

The aim of this study was to analyse sensitivity, specificity and predictive values of recently available MYC immunohistochemistry (IHC) against the currently standard diagnostic method, fluorescence in situ hybridisation (FISH) analysis. MYC IHC and FISH analyses were performed on 30 cases of diffuse large B cell lymphoma (DLBCL) with 80% or more Ki-67 index, one case of DLBCL transformed from follicular lymphoma, three cases of B cell lymphoma intermediate between DLBCL and Burkitt lymphoma (IM), six cases of Burkitt lymphoma (BL) and one case of reactive lymph node. The inclusion criteria of high Ki-67 index, more than 80%, was imposed to exclude dependence of MYC positivity on Ki-67 positivity.

B cell lymphoma, unclassifiable, with features intermediate between diffuse large B cell lymphoma and classical hodgkin lymphoma: diagnosis by fine-needle aspiration cytology.

A 58-year-old lady presented with mediastinal lymphadenopathy. A thoracoscopic ultrasound-guided fine-needle aspiration showed large atypical epithelioid cells arranged in cohesive sheets and dispersed as single cells with intact cytoplasm amid a background of lymphocytes and histiocytes. A cytological diagnosis of "a malignant neoplasm" was made, raising a broad list of differential diagnoses.