Artificial intelligence approach for detecting and classifying abnormal behaviour in older adults using wearable sensors.

The global population of older adults has increased, leading to a rising number of older adults in nursing homes without adequate care. This study proposes a smart wearable device for detecting and classifying abnormal behaviour in older adults in nursing homes. The device utilizes artificial intelligence technology to detect abnormal movements through behavioural data collection and target positioning.

Peripheral blood mononuclear cell respiratory function is associated with progressive glaucomatous vision loss.

Intraocular pressure (IOP) is currently the only modifiable risk factor for glaucoma and all licensed treatments lower IOP. However, many patients continue to lose vision despite IOP-lowering treatment. Identifying biomarkers for progressive vision loss would have considerable clinical utility.

Healthcare 5.0: A secure and distributed network for system informatics in medical surgery.

Introduction: Health records serve not only as a database of a patient's health history and treatment process but also as a crucial tool for doctors to diagnose and treat patients. However, the storage and sharing of these records are sensitive issues as they involve maintaining patient privacy and ensuring data transparency, security, and interoperability between different parties. Challenges to achieving these goals in the current surgical process can impact the allocation of medical resources and surgical outcomes.

Fine particle pollution during megafires contains potentially toxic elements.

Wildfires that raged across Australia during the 2019-2020 'Black Summer' produced an enormous quantity of particulate matter (PM) pollution, with plumes that cloaked many urban centres and ecosystems along the eastern seaboard. This has motivated a need to understand the magnitude and nature of PM exposure, so that its impact on both built and natural environments can be more accurately assessed. Here we present the potentially toxic fingerprint of PM captured by building heating, ventilation, and air conditioning filters in Sydney, Australia during the peak of the Wildfires, and from ambient urban emissions one year later (Reference period).

α-Synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells: an proof of concept study.

Caudo-rostral migration of pathological forms of α-synuclein from the gut to the brain is proposed as an early feature in Parkinson's disease pathogenesis, but the underlying mechanisms remain unknown. Intestinal epithelial enteroendocrine cells sense and respond to numerous luminal signals, including bacterial factors, and transmit this information to the brain via the enteric nervous system and vagus nerve. There is evidence that gut bacteria composition and their metabolites change in Parkinson's disease patients, and these alterations can trigger α-synuclein pathology in animal models of the disorder.

Parentage influence on gene expression under acidification revealed through single-embryo sequencing.

The dissolution of anthropogenic carbon dioxide (CO ) in seawater has altered its carbonate chemistry in the process of ocean acidification (OA). OA affects the viability of marine species. In particular, calcifying organisms and their early planktonic larval stages are considered vulnerable.

Green supply chain, green leadership, consumer preferences, sustainability attitudes, and sustainable business advantage: a case of Vietnamese textile industry.

Surging environmental issues confiscate stakeholders' attention due to growing competition. Sustainable performance in this regard is viewed as a suitable tool because it not only gauges firm's financial performance but also covers social and environmental areas. However, sustainable performance cannot be achieved without creating sustainable business advantage.

Digital technology and its application in supply chain management: new evidence from China's economy.

The purpose of this article is to investigate the influence that practices using information technology (IT) have on the development of a competitive advantage across the supply chain. An organization has a competitive advantage when it has qualities that give the required foundations for it to separate itself from other organizations that are also in its industry. Pressure is applied to the corporate environment as a result of competition and ongoing changes, such as the introduction of new products and technical advancements, the decline of product lifestyles, and the proliferation of products.

Green finance, renewable energy investments, natural resources, and sustainable economic advancements in China: evidence from pre-post COVID-pandemic.

Since the start of twenty-first century, the globe has bumped into several crises, such as the sudden rise of oil prices in 2003 and the large-scale global financial crisis in 2007-2008. However, the most recent COVID-19 outbreak has slowed fiscal progress and initiated instability in the prices of commodities-based natural resources. The instability of prices of natural resources attracted the focus of academicians and policymakers.

The Role of Mitophagy in Glaucomatous Neurodegeneration.

This review aims to provide a better understanding of the emerging role of mitophagy in glaucomatous neurodegeneration, which is the primary cause of irreversible blindness worldwide. Increasing evidence from genetic and other experimental studies suggests that mitophagy-related genes are implicated in the pathogenesis of glaucoma in various populations. The association between polymorphisms in these genes and increased risk of glaucoma is presented.

Platelet function in neonates and children.

Platelets are major regulators of haemostasis and coagulation. The primary role of platelets in coagulation is to form a stable clot and stop bleeding. Studies of platelet phenotype and function in neonates and children have been restricted by the large volumes required for many common platelet function tests such as platelet aggregometry.

Natural resource volatility and financial development during Covid-19: Implications for economic recovery.

Demand for natural resources is constant, while the prices of natural resources increase day-by-day, which has a significant impact on financial development and economic activity. Thus, the study intends to test the association of natural resource volatility and financial development, in order to recommend policies for economic recovery. The study acquires and analyses data for the N11 economies.

The Progress of Smart Elderly Care Research: A Scientometric Analysis Based on CNKI and WOS.

To reduce the burden caused by an increased elderly population and to provide efficient service resources, scholars worldwide have proposed and applied smart elderly care. This paper summarizes the hotspots of the existing literature and explores the research frontiers to ignite future research. CiteSpace software was used to conduct a scientometric analysis of high-quality literature collected from both the China National Knowledge Infrastructure (CNKI) and the Web of Science (WOS).

The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines.

Sequence variants or mutations in the GBA gene are numerically the most important risk factor for Parkinson disease (PD). The GBA gene encodes for the lysosomal hydrolase enzyme, glucocerebrosidase (GCase). GBA mutations often reduce GCase activity and lead to the impairment of the autophagy-lysosomal pathway, which is important in the turnover of alpha-synuclein, accumulation of which is a key pathological hallmark of PD.

Relating Sustainable Business Development Practices and Information Management in Promoting Digital Green Innovation: Evidence From China.

Digital green innovations are being implemented in manufacturing to help organizations achieve sustainability by adopting sustainable development practices (SDPC). However, little is known about the impact of the information management process (IMP) on organizations' digital green innovation. To address this gap, we devised a multidimensional framework based on the resource-based view (RBV) theory that serves as a basis for sculpting how the IMP captured and sustained organizational digital green innovation via SDPCs.

Modeling COVID-19 Impact on Consumption and Mobility in Europe: A Legacy Toward Sustainable Business Performance.

This article has explored the impact of coronavirus disease 2019 (COVID-19)-induced decline in consumer durables and mobility on nitrogen dioxide (NO) emission in Europe by providing empirical and graphical justifications based on consumer price index (CPI) and gross domestic product (GDP) deflator indexes. The empirical estimations show that carbon dioxide (CO) and NO emission along with other greenhouse gases drastically decreased in the wake of COVID-19-induced lockdowns and decrease in the demand of consumer goods in Europe. This means that COVID-19 improved environment in the European region.

Towards a sustainable online peer learning model based on student's perspectives.

The outbreak of the COVID-19 pandemic has fundamentally shifted learning from the traditional classroom approach to online learning. As such, this study used a revision centre as a case study to develop the factors that contribute to the theoretical framework of online peer learning in the higher education sector due to COVID-19. This study also explores the integrated effects of online peer learning on students and investigates whether advanced information technology creates new opportunities or additional burdens for students in adopting online peer learning environments.

Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly.

Mitotic centrosomes are formed when centrioles start to recruit large amounts of pericentriolar material (PCM) around themselves in preparation for mitosis. This centrosome "maturation" requires the centrioles and also Polo/PLK1 protein kinase. The PCM comprises several hundred proteins and, in Drosophila, Polo cooperates with the conserved centrosome proteins Spd-2/CEP192 and Cnn/CDK5RAP2 to assemble a PCM scaffold around the mother centriole that then recruits other PCM client proteins.

Determinants of Social Commerce Usage and Online Impulse Purchase: Implications for Business and Digital Revolution.

Since their introduction in the early 2000s, the use of social networking websites has exploded. Many businesses are seeing increased revenue due to their social commerce strategy. Despite the popularity of social commerce websites, some consumers are still hesitate to use them.