Objectives: To stratify MI risk reduction in those treated with a TNF inhibitor for psoriasis only, psoriatic arthritis only, or both psoriasis and psoriatic arthritis.
Design: Retrospective cohort study.
Setting: Between January 1, 2004 and November 30, 2010.
Objective: We sought to assess whether the type of TNF inhibitor therapy (soluble receptor versus monoclonal antibody) has an effect on MI risk; and determine whether length of TNF inhibitor therapy has an effect on MI risk.
Design: Retrospective cohort study.
Setting: Between January 1, 2004 and November 30, 2010.
The purpose of this study was to determine the level of care of Parkinson's disease patients based on the 10 American Academy of Neurology quality measures. We reviewed 1,367 charts and final analysis was completed on 123 subjects. A total of 1,461 outpatient neurology visits from 33 neurologists were reviewed and 544 were included in the final analysis.
View Article and Find Full Text PDFOBJECTIVE To assess whether patients with psoriasis treated with tumor necrosis factor (TNF) inhibitors have a decreased risk of myocardial infarction (MI) compared with those not treated with TNF inhibitors. DESIGN Retrospective cohort study. SETTING Kaiser Permanente Southern California health plan.
View Article and Find Full Text PDFBackground: Previous studies provide evidence that there is a greater frequency of autoimmune diseases among patients with psoriasis than in the general population.
Objective: This study examined the association between psoriasis and 21 common autoimmune diseases, specified a priori.
Methods: A retrospective cohort study was conducted among persons who were members of Kaiser Permanente Southern California from 2004 to 2011.
J Allergy Clin Immunol
November 2011
Background: The association between obesity and asthma severity and control in children is not well understood.
Objective: The objective of this study was to examine the association of childhood body mass index (BMI) percentile for age of 85% or greater with the number of β-agonist canisters dispensed, corticosteroid courses, emergency department visits, and hospitalizations for asthma.
Methods: A retrospective cohort of 32,321 children aged 5 to 17 years and given a diagnosis of asthma who received at least 1 asthma (controller or rescue) medication and were enrolled in Kaiser Permanente from 2004-2008 was identified.
Ann Allergy Asthma Immunol
August 2010
Background: The intermittent unavailability of penicilloyl-polylysine since September 2000 has focused interest on commercial anti-penicillin IgE fluorometric enzyme immunoassay (FEIA) tests to evaluate penicillin allergy. There has been no published comparison of commercial anti-penicillin IgE FEIAs and penicillin skin testing performed in the United States.
Objective: To determine whether the current commercial anti-penicillin IgE FEIAs can replace or augment penicillin skin testing and oral challenges when evaluating individuals with a history of penicillin allergy for future therapeutic penicillin tolerance.
Red wine contains polyphenol antioxidants that inhibit colorectal cancer (CRC) development in animal studies. We investigated the effect of red wine intake on risk of CRC in the California Men's Health Study (CMHS). CMHS is a prospective, multiethnic cohort of middle-aged men who were members of the Kaiser Permanente (KP) California Health Plans and completed study questionnaires between 2002-2003.
View Article and Find Full Text PDFRed wine contains polyphenol antioxidants that inhibit prostate cancer development in animal studies. We investigated the effect of red wine intake on the risk of prostate cancer using data prospectively collected in the California Men's Health Study (CMHS). CMHS is a multiethnic cohort of 84,170 men aged 45-69 years who were members of the Kaiser Permanente Southern and Northern California Health Plans.
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