Combined simultaneous transcranial and transsphenoidal resection of large-to-giant pituitary adenomas.

Background: While large-to-giant pituitary adenomas (PAs) may be safely removed by experienced surgeons through a single route, the procedure is technically challenging. We present the outcome of a simultaneous combined transcranial and transsphenoidal approach and discuss its applications.

Methods: A retrospective review was conducted on 12 consecutive patients.

Growing skull fracture in an adult nine years after blunt head trauma.

Growing skull fracture (GSF) is an uncommon but well recognized complication of calvarial fracture in infancy and early childhood. The condition is rare in adults, and involvement of the skull base in this group of patients affects mostly the orbital roof. We present a patient with an unusual GSF involving the cribriform plate in a 37-year-old man who presented with late-onset epilepsy and recurrent meningitis 9 years after the initial trauma.