Publications by authors named "Kwok W Im"
Unlabelled: Individuals with SHANK3 mutations have severely impaired receptive and expressive language abilities. While brain responses are known to be abnormal in these individuals, the auditory cortex response to sound has remained largely understudied. In this study, we document the auditory cortex response to speech and non-speech sounds in the novel Shank3-deficient rat model.
View Article and Find Full Text PDFIndividuals with Rett syndrome have greatly impaired speech and language abilities. Auditory brainstem responses to sounds are normal, but cortical responses are highly abnormal. In this study, we used the novel rat Mecp2 knockout model of Rett syndrome to document the neural and behavioral processing of speech sounds.
View Article and Find Full Text PDFArticle Synopsis
- Kids with autism often have trouble with talking and understanding speech.
- Giving lots of practice and help can make their speech better and help their brains respond to sounds.
- Researchers studied rats that were affected by a drug before they were born and found that with training, these rats got much better at hearing and recognizing different sounds.
Article Synopsis
- Fragile X syndrome is the most common inherited cause of intellectual disability and can also lead to autism.
- In a study with rats that have fragile X syndrome, researchers found that their brains did not process speech sounds as well as normal rats, even though they could still tell the sounds apart.
- The study suggests that problems in a specific part of the brain related to emotions could explain why people with fragile X syndrome have trouble with emotional control.