ANNIE: integrated de novo protein sequence annotation.

Function prediction of proteins with computational sequence analysis requires the use of dozens of prediction tools with a bewildering range of input and output formats. Each of these tools focuses on a narrow aspect and researchers are having difficulty obtaining an integrated picture. ANNIE is the result of years of close interaction between computational biologists and computer scientists and automates an essential part of this sequence analytic process.

A nurse-managed smoking cessation intervention during pregnancy.

Objective: To evaluate the effectiveness of a nurse-managed smoking cessation intervention in an outpatient setting among pregnant women who smoked.

Design: Prospective; control group participants' cessation rates were assessed 6-12 weeks after clinic contact. They were compared to cessation rates for subsequent intervention participants 6-12 weeks after receiving a nurse-managed smoking cessation intervention.