Cutaneous Plasmacytoma: Metastasis of Multiple Myeloma at the Fracture Site.

Multiple myeloma (MM) can be defined as a malignancy with monoclonal plasma cell proliferation. A 66-year-old man presented with pruritic erythematous to purplish plaque grouped nodule with black pigmentations and purpura on the right forearm. The patient was diagnosed with MM about five years prior to the visit at our hospital.

Self-Assembled Dendritic Pt Nanostructure with High-Index Facets as Highly Active and Durable Electrocatalyst for Oxygen Reduction.

The durability issues of Pt catalyst should be resolved for the commercialization of proton exchange membrane fuel cells. Nanocrystal structures with high-index facets have been recently explored to solve the critical durability problem of fuel cell catalysts as Pt catalysts with high-index facets can preserve the ordered surfaces without change of the original structures. However, it is very difficult to develop effective and practical synthetic methods for Pt-based nanostructures with high-index facets.

Eccrine Squamous Syringometaplasia Associated with Pelubiprofen Therapy.

Eccrine squamous syringometaplasia (ESS) is a histologically distinctive skin eruption occurring predominantly in acral or intertriginous areas presenting as erythematous macules, papules or patches. The etiology of ESS remains unclear, but it is usually reported in patients receiving chemotherapy for various malignant neoplasms. To date, only two cases of ESS associated with non-steroidal anti-inflammatory drugs (NSAIDs), which has distinctive clinical features and pathogenesis, have been reported in the literature.

Increased risk of comorbid rheumatic disorders in vitiligo patients: A nationwide population-based study.

Vitiligo is a common acquired depigmentation disorder. Previous studies have shown that vitiligo is associated with a variety of autoimmune disorders. However, a large-scale epidemiological study focused on comorbid rheumatic disorders has not been undertaken.

Hidden Pictures of Kaposi's Sarcoma in Psoriatic Lesions: A Diagnostic Challenge.

Kaposi's sarcoma is a multifocal proliferative vascular tumor involving the skin and other organ and psoriasis is a chronic cutaneous disease with papules and plaques with white scale. Development of Kaposi's sarcoma in psoriasis patients has been reported rarely. A 71-year-old man presented with multiple brownish to violaceous plaques on both feet and arms which were found 4 months ago.

Subsequent vitiligo after hematopoietic stem cell transplantation: A nationwide population-based cohort study from Korea.

Background: Subsequent vitiligo after hematopoietic stem cell transplantation (HSCT) has been described sporadically in case series.

Objective: To investigate the incidence and risk factors of subsequent vitiligo after HSCT.

Methods: A nationwide, population-based cohort study was performed using the Korean National Health Insurance Claims Database from 2009 to 2013.

Inflammatory bowel disease is associated with an increased risk of inflammatory skin diseases: A population-based cross-sectional study.

Background: Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract attributed to aberrant activity of the immune system. Increasing evidence suggests that patients with IBD are at an increased risk of inflammatory skin diseases (ISDs).

Objective: We sought to clarify the association between IBD and ISDs using a nationwide health claims database maintained in Korea.

The Accuracy of Ultrasonography on the Location of Lipomas in the Forehead.

Background: Preoperative recognition of tumor plane is important to avoid surgical complications in surgeries involving the scalp. Ultrasonography is a useful diagnostic tool to detect the depth of tumor noninvasively. However, some findings are not always in accordance with the actual locations of lipomas, especially in the forehead.

A simple synthesis of urchin-like Pt-Ni bimetallic nanostructures as enhanced electrocatalysts for the oxygen reduction reaction.

The synthesis of urchin-like Pt-Ni bimetallic nanostructures is achieved by a controlled one-pot synthesis. Pt-Ni nanostructures have superior oxygen reduction reaction activities in both with and without specific anion adsorption electrolytes due to the geometric and alloying effects.

Phototrichogram analysis of normal scalp hair characteristics with aging.

Background: Phototrichogram analysis of normal scalp hair characteristics in Asian populations is not well characterized.

Objective: To investigate the normal hair characteristics of South Koreans using a phototrichogram.

Methods: We enrolled 674 males and 683 females between the ages of 10 and 69.

Chemical tuning of electrochemical properties of Pt-skin surfaces for highly active oxygen reduction reactions.

Pt-skin surfaces were successfully fabricated by the chemical deposition of additional Pt on corrugated Pt-Ni nanoparticles with Pt-skeleton surfaces. Compared to the Pt-skin formed by heat annealing, the chemically-tuned Pt-skin had a higher Pt coordination number and surface crystallinity, which resulted in superior ORR activity and durability.

Correlation between platinum nanoparticle surface rearrangement induced by heat treatment and activity for an oxygen reduction reaction.

Heat treatment of nanoparticles could induce the surface rearrangement for more stable facet exposure induced by thermodynamics. By changing the heat treatment environment, we confirmed the correlation between the oxygen reduction activity and the effect of surface oxide and the degree of surface rearrangement of Pt nanoparticles. Native surface oxide was not a critical factor for oxygen reduction activity.

Surface structures and electrochemical activities of Pt overlayers on Ir nanoparticles.

Pt overlayers were deposited on carbon-supported Ir nanoparticles with various coverages. Structural and electrochemical characterizations were performed using transmission electron microscopy (TEM), X-ray diffraction, high-resolution powder diffraction (HRPD), X-ray photoelectron spectroscopy (XPS), X-ray absorption near-edge spectroscopy (XANES), cyclic voltammetry (CV), CO stripping voltammetry, and N2O reduction. The surface of Ir nanoparticles was covered with Pt overlayers with thickness varying from the submonolayer scale to more than two monolayers.

Prevalence of atopic dermatitis among Korean adults visiting health service center of the Catholic Medical Center in Seoul Metropolitan Area, Korea.

The point prevalence of atopic dermatitis (AD) among Korean adults visiting the Health Service Center for health check-ups was assessed. AD was diagnosed based on the questionnaires filled by patients and through physical examination by dermatologists. A total of 3,563 persons completed the questionnaires, and 2,032 persons were examined by the dermatologists.

Peptide deformylase inhibitors with non-peptide scaffold: synthesis and structure-activity relationships.

Peptide deformylase (PDF), which removes the formyl group at the N-terminal methionine residue of nascent protein, has been recognized as a potent target for antibacterial therapy. We report herein the synthesis and structure-activity relationship studies of non-peptide PDF inhibitors.

The keratin-14 expression in actinic keratosis and squamous cell carcinoma: is this a prognostic factor for tumor progression?

Purpose: Actinic keratosis (AK) is an incipient form of cutaneous squamous cell carcinoma (SCC). We determined if the pattern of expression of keratin-14 (K14) is a factor for tumor progression in AK and SCC.

Materials And Methods: Eighteen sections from the tissues of 16 patients were stained with anti-K14 antibody and p16(INK4a).

Peptide deformylase inhibitors with retro-amide scaffold: synthesis and structure-activity relationships.

Peptide deformylase (PDF) is a metalloprotease catalyzing the removal of a formyl group from newly synthesized proteins. Thus inhibition of PDF activity is considered to be one of the most effective antibiotic strategies. Reported herein are the synthesis and structure-activity relationship studies of retro-amide inhibitors based on actinonin, a naturally occurring PDF inhibitor.

Kaposi sarcoma after corticosteroid therapy for idiopathic thrombocytopenic purpura.

Kaposi sarcoma (KS) is a multifocal vascular neoplasm most commonly seen in association with human immunodeficiency virus infection. However, KS has also been reported in patients treated with immunosuppressive agents. However, it is very rare to find KS in association with idiopathic thrombocytopenic purpura (ITP).

The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3'-phosphoadenosine 5'-phosphosulfate reveals a new ligand-binding mode.

Bacterial phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate step in the coenzyme A (CoA) biosynthetic pathway. It catalyzes the reversible transfer of an adenylyl group from ATP to 4'-phosphopantetheine (Ppant) to form dephospho-CoA (dPCoA) and pyrophosphate. Previous structural studies have revealed how several ligands are recognized by bacterial PPATs.