Acute Osteomyelitis in the Hand Due to Dog Bite Injury: A Report of 3 Cases.

As many people keep small dogs as pets, dog bites are common injuries, accounting for approximately 80%-90% of all animal bite injuries. These injuries usually occur on the upper extremities, most commonly on the fingers. Most of these injuries appear as simple lacerations or abrasions of the skin.

Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model.

Ginsenoside, one of the active compounds in Panax ginseng, inhibits tumor growth factor-beta 1 (TGF-β1) and reduces the level of collagen type 1. Ginsenoside Rb1 promotes burn wound healing. Our study evaluated the effects of ginsenoside Rb1 on hypertrophic scar remodeling.

Effect of endogenous bone marrow derived stem cells induced by AMD-3100 on expanded ischemic flap.

The purpose of this study was to devise an expanded ischemic flap model and to investigate the role of AMD-3100 (Plerixafor, chemokine receptor 4 inhibitor) in this model by confirming its effect on mobilization of stem cells from the bone marrow. Male Sprague-Dawley rats were used as an animal research model. The mobilization of stem cells from the bone marrow was confirmed in the AMD-3100-treated group.

Glomus tumors: symptom variations and magnetic resonance imaging for diagnosis.

Background: The typical clinical symptoms of glomus tumors are pain, tenderness, and sensitivity to temperature change, and the presence of these clinical findings is helpful in diagnosis. However, the tumors often pose diagnostic difficulty because of variations in presentation and the nonspecific symptoms of glomus tumors. To the best of our knowledge, few studies have reported on the usefulness of magnetic resonance imaging (MRI) in diagnosing glomus tumors in patients with unspecific symptoms.

Better survival of random pattern skin flaps through the use of epigallocatechin gallate.

Background: Surgical skin flaps are useful, but flap necrosis is a common problem. Epigallocatechin gallate (EGCG), the major polyphenol of green tea, has been investigated as a neovascularization agent to counteract necrosis.

Objectives: To evaluate the effect of EGCG on random pattern skin flap survival.

Human giant congenital melanocytic nevus exhibits potential proteomic alterations leading to melanotumorigenesis.

Background: A giant congenital melanocytic nevus (GCMN) is a malformation of the pigment cells. It is a distress to the patients for two reasons: one is disfigurement, and the other is the possibility of malignant changes. However, the underlying mechanisms of the development of GCMN and melanotumorigenesis in GCMN are unknown.

Effect of human adipose derived stem cells on scar formation and remodeling in a pig model: a pilot study.

Background: Adipose-derived stem cells (ASCs) have positive effects in the wound healing process.

Objective: To clarify whether ASCs positively mitigate scar formation in the wound remodeling process.

Materials And Methods: Full-thickness skin defects were created on the dorsal skin of Yorkshire pigs.

The fate of long-standing port-wine stain and its surgical management.

Background: A port-wine stain begins with thin macular lesions and eventually becomes hypertrophic and forms nodules. Although laser therapy for port-wine stain is a safe treatment modality that has been well-established, the long-standing port-wine stain has a tendency to respond less well to laser treatment. The authors performed total surgical resections of long-standing port-wine stain in the facial region, and attempted to clarify the histomorphologic changes.

Determination of adipose-derived stem cell application on photo-aged fibroblasts, based on paracrine function.

Background Aims: Adipose-derived stem cells (ASC) are known to be able to restore injured tissue via differentiation and paracrine effects. In this study, we investigated the effect of ASC on photo-aged human dermal fibroblasts (HDF) based on paracrine function. In particular, we wanted to determine a more effective method of ASC application and the fate of the photo-aged fibroblasts.

Effects of human cord blood mesenchymal stem cells on cutaneous wound healing in leprdb mice.

Purpose: In the present study, we used the diabetic mouse as a model of delayed wound healing to investigate the effects of human cord blood mesenchymal stem cells (CB-MSC) on wound healing.

Methods: A delayed wound healing model was used by db/db mice. Study models were divided by an injection of human CB-MSC with phosphate buffered solution (PBS) by a different method.

Efficacy of antiadhesion barrier solution on periimplant capsule formation in a white rat model.

Antiadhesive barrier solution (AABS) has been proven to prevent intraabdominal adhesion by reducing inflammation and fibrosis formation. Because this mechanism can also be applied to capsule formation after the breast implant insertion, we hypothesize that AABS can reduce capsular contraction and evaluate the efficacy of AABS on perisilastic implant capsule formation after submuscular insertion. A silicone block was inserted beneath the panniculus carnosus muscle in 10 rats.

Effect of recombinant human epidermal growth factor against cutaneous scar formation in murine full-thickness wound healing.

A visible cutaneous scar develops from the excess formation of immature collagen in response to an inflammatory reaction. This study examined the role of epidermal growth factor (EGF) in the formation of cutaneous scars. Twenty Crl:CD-1 (ICR) mice were used and 2 full-thickness skin wounds were made on the dorsum of each mouse.

Superior lipolytic effect of the 1,444 nm Nd:YAG laser: comparison with the 1,064 nm Nd:YAG laser.

Background And Objectives: Recently developed laser lipolysis systems have been disappointing because they require more time to remove the same amount of fat than other liposuction methods. A new Nd:YAG laser has been introduced that uses the 1,444 nm wavelength, better absorbed by fat.

Study Design/materials And Methods: This study consisted of two protocols.

Gossypiboma after mandibular contouring surgery.

Background: Gossypiboma is derived from the Latin word gossypium, meaning cotton, and it means a postoperatively retained foreign body used in operations. Several cases of gossypiboma have been reported especially after abdominal surgery, but there has not been any reported case in plastic surgery. Mandibular contouring surgery cannot ensure a view wide enough to avoid injury to surrounding structures such as a facial artery and a retromandibular vein.

Hypopharyngeal reconstruction using remnant narrow pharyngeal wall as omega-shaped radial forearm free flap.

Purpose: There have been numerous attempts to use pharyngoesophageal reconstruction to restore swallowing function. Much controversy exist over reconstruction after total or partial pharyngectomy, and there is also debate over whether to continue with the reconstructive procedure with a narrow strip of remnant mucosa or complete it after total pharyngectomy. We analyzed the utility of omega-shaped radial forearm free flap (RFFF) using the narrow remnant posterior pharyngeal wall.

The effect of botulinum toxin A on skin flap survival in rats.

This study examines the role of botulinum toxin type A (BoTA) in preventing the collapse of the peripheral vessels in the cutaneous flap and in increasing the survival of the flap. Because BoTA cleaves the SNAP-25 protein, the release of vasoconstriction cotransmitters as well as acetylcholine would be blocked. Dorsal skin flaps in rats were elevated and returned to the original position.

Correlation between changes of medial rectus muscle section and enophthalmos in patients with medial orbital wall fracture.

Background: Enophthalmos is the most distressing and common complication of the blow-out fracture. In spite of well-established indications for early operative repair of orbital fracture, 7-10% of patients treated non-operatively develop enophthalmos. There have been reports on the correlation between changes of orbital bone and enophthalmos; however, there is no report on muscle changes in computed tomography (CT) in medial blow-out fracture.

Infrabrow excision blepharoplasty: applications and outcomes in upper blepharoplasty in Asian women.

Background: To avoid the somewhat operated look while effectively resolving shortcomings inherent in the conventional blepharoplasty technique, the authors propose an infrabrow excision blepharoplasty as a satisfying and useful alternative. The authors' experience during a 3-year period is presented and reviewed.

Methods: Sixty-four patients were operated on by infrabrow excision blepharoplasty.

Pectoralis major-rectus abdominis bipedicled muscle flap in the treatment of poststernotomy mediastinitis.

Objectives: Although the incidence of infected sternotomy wounds after median sternotomy for cardiovascular surgery is relatively low (0.5% to 5%), it is associated with significant morbidity and a long period of treatment. Today, muscle flaps, such as the pectoralis major or the rectus abdominis, are widely accepted as a mainstay of reconstructive options.

Inferior gluteal artery perforator flap: a viable alternative for ischial pressure sores.

The ischial area is by far the most common site for pressure sores in wheelchair-bound paraplegic patients, because most of the pressure of the body is exerted on this area in the seated position. Even after a series of successful pressure sore treatments, the site is very prone to relapse from the simplest everyday tasks. Therefore, it is crucial to preserve the main pedicle during primary surgery.

Analysis of 30 breast implant rupture cases.

Breast implants used for augmentation mammoplasty or breast reconstruction could rupture from various causes such as trauma or spontaneous failure. The objectives of this study were to investigate the relationships between the causes of implant rupture and the degree of capsular contracture, and then to evaluate the relative efficacies of specific signs on magnetic resonance imaging (MRI) known to be beneficial for diagnosing the rupture. A retrospective review identified patients with prosthetic implant rupture or impending rupture treated by the senior author.

Standardization of flap design for oropharyngeal reconstruction after cancer ablation surgery.

A variety of residual defects containing many sulci and fossae in the oropharyngeal cavity make it extremely difficult to achieve an adequate flap design as well as the functional reconstruction of the complex defects after ablation surgery for oropharyngeal tumors. This study attempted to standardize flap design for the different types of defects in order to produce a better functional reconstruction of intra-oral defects. The oropharyngeal defects were classified into 6 Zones.

Coverage of difficult wounds around the knee joint with prefabricated, distally based sartorius muscle flaps.

The coverage of soft-tissue defects around the knee joint presents a difficult challenge to the reconstructive surgeon. Various reconstructive choices are available depending on the location, size, and depth of the defect relative to the knee joint. However, the knee joint frequently accompanies injuries to the lower leg that may limit the use of muscle flaps, especially the gastrocnemius muscle.