[Experience of high frequency electric welding in endocrine surgery].

The comparative analsis of the effectiveness of surgical interventions performed by the standard method and using electric welding technology in endocrine surgery was hold. Compared duration of surgery, amount of intraoperatve blood loss, frequency of intra- and early postoperative complications. Found that the use of weding technology ensures shorter duration of surgery, on average by 30%, amount of blood loss--by 20-50%, the frequency of intra- and early postoperative complications.

[Clinical and epidemiological aspects of medullary thyroid carcinoma in Ukraine].

Analyzed data from 232 patients with medullary thyroid carcinoma who were treated in the surgical department of the Institute from 1979 to 2012 (inclusive). Found that the analyzed cohort of patients to meet other samples in such characteristics as age of patients and the distribution of the forms of the disease (sporadic, familial, in the syndrome MEN-2B). At the same time it is shown that the number of patients with sporadic medullary carcinoma from the end of the century the alien has increased significantly mainly due to the increase in the number of female patients.

[Laparoscopic adrenalectomy in surgery of the adrenal gland diseases].

In 2002-2012 yrs in The Department of Laparoscopic Surgery and Choledocholithiasis laparoscopic adrenalectomy (LA) for various adrenal gland diseases was done in 94 patients. The operation time while doing right-sided and left-sided LA have had constituted, accordingly, at average (73.6 +/- 12.

[The use of phytotherapy for treatment of thyroid diseases].

The main tasks during treatment of hyperplastic thyroid diseases--to stop the growth of thyroid nodules; compensation of hypothyrosis; normalization of thyroid size. One of the perspective methods in combine therapy of diffuse and mix goiter is a phytotherapy. The most often for thyroid diseases we have used the plant drug Polentilla alba, which on Ukrainian market was registered as "Alba".

[Application of high frequency electric welding in adrenal surgery. Current state and prospects].

In 14 patients underwent open adrenalectomy with high-frequency electric welding application (I group), in 8 - open adrenalectomy (II group). The two groups were compared: duration of surgery, blood loss, postoperative pain intensity, duration of postoperative hospitalization, the frequency of intra-and postoperative complications, histological changes in tissues. The advantages of open adrenalectomy with high-frequency electric welding application feel less duration of surgery and estimated blood loss, lack of necrosis in the surrounding tissues and foreign bodies in the wound, reducing the trauma of surgery, improving rehabilitation.

[The role of computer tomography in differential diagnostic of incidentalomas adrenal glands].

The possibilities of computer tomography (CT) for differential diagnosis of adrenal incidentalomas (AI) were investigated. CT was done for 157 patients with AT: 17--with malignant adrenal tumors (MAT) and 70--with benign adrenal tumors (BAT) (61--adrenocortical adenoma, 5--cyst, 3--hematoma, 1--myelolipoma). CT--main method of topic diagnostic for AI, which allow to make assumption about potential malignancy AI in 76.

[Clinical-laboratory characteristic of adrenal incidentalomas].

Last years while applying modern methods of topic diagnosis the adrenal glands tumors are revealed as an "incidental finding", so called "adrenal incidentalomas" (AI). It is necessary to investigate hormonal activity of these complaints for conduction of timely and radical treatment. The authors have analyzed of complaints, the objective and laboratory investigations data, which were conducted in 122 patients, suffering AI.

[Surgical treatment of adrenocortical cancer: significance of systematic lymphodissection].

Comparative efficacy of radical methods of surgical intervention for adrenocortical cancer (ACC) with lymphodissection (LD) and without it was studied. There were operated on 280 patients for primary ACC. Adrenalectomy (AE) with en bloc excision of tumor and systematic lymph nodes dissection (paranephral, left-side paraaortal and the right-side paracaval collectors) constitutes the optimal surgical procedure.

[Laparoscopic interventions for adrenal gland tumor].

Clinical course, hormonal characteristics and efficacy of rehabilitation were studied by the authors in 12 patients with suprarenal gland tumor, operated, using minimally invasive endoscopic intervention--laparoscopic adrenalectomy (LA). Efficacy, indications, contraindications, role of LA in the treatment of surgical adrenal diseases were analyzed. LA is characterized by invasiveness and traumaticity, adequate radicalism, quick rehabilitation, and good remote results.

[Using magnetic-resonance tomography in differential diagnosis of the adrenal glands malignant tumors].

Possibilities of application of magnet-resonance tomography (MRT) for differential diagnosis of the adrenal glands tumors were studied up. MRT was conducted to 39 patients with adrenal glands tumors, including 22 - with malignant adrenal gland tumor, 17 - with benign tumor of adrenal gland. MRT constitutes the most effective method of topic diagnosis of the adrenal glands tumor, owes multipurpose possibilities, do not deliver radiation load, permits to visualize the vessels without the contrast media usage.

[Using ultrasound investigation in differential diagnosis of adrenal malignant tumors].

Possibilities of ultrasound investigation (USI) application for differential diagnosis of the suprarenal glands tumors (SGT) were studied. USI was conducted in 169 patients with SGT, including 95 with malignant tumors of suprarenal glands (MTSG) and 64--with benign SGT. USI constitutes the main method of screening, permitting to reveal SGT in 90.

[The choice of operative intervention in combined treatment of malignant tumors of the adrenal glands].

Comparative efficacy of various kinds of surgical treatment for malignant tumors of adrenal glands (MTAG) was studied. Traumaticity of various kinds of operations was estimated. There were operated on 318 patients, suffering MTAG: in 280--primary interventions were performed and in 38--reoperations.

[The role of computer tomography in differential diagnosis of benign and malignant tumors of the adrenals cortex].

Possibilities of computer tomography (CT) application for differential diagnosis of tumors of the adrenal cortex (TAC) were studied. CT was conducted in 157 patients with TAC, including 75--with malignant (MTAC), 82--with benign (BTAC), permitting to revealed MTAC in 76% patients. In 17.

[Chloditane therapy of adrenocortical cancer].

Adrenocortical cancer (ACC) is a rare and aggressive tumor often diagnosed at the late stage of its development. Treatment with adrenocorticotoxic drug chloditane has been applied decades, but in spite of this we see scrupulous investigations of using chloditane in a complex treatment of ACC be carried out. The author has analyzed the following schemes of chloditane use: in preoperative period, after the potentially radical and non-potentially radical surgery, for symptomatic treatment.

[The surgical treatment of malignant adrenal chromaphinomas].

Pheochromoblastoma (PHB) is a tumor developing from adrenal medulla and characterized by severe course and high mortality level (15%). The severity of patients' state determined not only by presence of cancerous growth, but also due to catecholamine hyperproduction. The author has analyzed the results of surgical treatment of 60 patients with PHB, which were in surgical clinic during 1968-2002 y.

[Application of the puncture biopsy in diagnosis of malignant tumors of suprarenal glands].

Possibilities of application of the fine-needle aspiration puncture biopsy (FNAPB) in diagnosis of suprarenal glands tumors were studied. Of 43 patients, to whom FNAPB was performed, in 27 the suprarenal gland tumor was diagnosed, in 11--renal tumor, in 5--the puncture biopsy material occurred noninformative. Of 27 patients with tumor of suprarenal gland in 15 it was malignant, in 11--benign adenoma and cyst of suprarenal gland were revealed.

[Recurrent malignant tumors of the adrenal glands: treatment and prognosis].

The malignant adrenal tumors (MAT) have aggressive trend and inclined to often recurrences and early metastasis. The author has analyzed the causes of the recurrences of MAT in 292 patients which have been treated in the clinic. The recurrences of MAT were shown to originate rather from adrenal cortex than from adrenal medulla.

[Classification of malignant tumors of suprarenal glands].

The extent of diagnostic possibilities of medical technique, permitting to reveal the majority of suprarenal tumors, and the most modem information technologies as well demands creation of the suprarenal tumors applicable classification, well-adopted for physician in practice and also for scientist dealing with analysis of the investigation results in these pathology. Taking into account hormonal activity of majority of tumors, influencing the patients management tactic, the authors propose the insight on suprarenal tumor diagnosis of their own.

[Analysis of local lymphogenic spreading of malignant adrenal tumors].

The effectivity of the treatment of malignant adrenal tumors (MAT) depends on primary complete tumor resection with its regional metastases (RM). The possible regional metastases of malignant adrenal tumors in 257 patients have been studied. One third of the patients were diagnosed with regional metastases.

[Malignant tumors of the adrenal glands without hormonal activity].

An increase in number of silent adrenal tumors is being observed by frequently using computer tomography and other modern diagnostics. All these tumors have to be diagnosed for their malignancy potential and hormonal activity to perform timely and curative treatment. The author has analyzed the results of treatment of 90 patients with malignant non-hormone producing adrenal tumors.

[Analysis of the results in pheochromoblastoma treatment].

Results of operative treatment of 60 patients with pheochromoblastoma were analyzed. Surgical method of treatment is the most effective one. Lumbotomic extraperitoneal access is the method of choice.

[Analysis of postoperative recurrence of malignant tumors of adrenal glands].

Malignant tumors of suprarenal glands (MTSG) are characterized by aggressive course, inclination to recurrences and early metastatic spreading. Causes of the recurrence occurrence of MTSG were analyzed in 292 patients. There was revealed more frequent recurrence of tumor of the adrenal gland cortical substance than of medullary substance.

[Features of clinical presentation of malignant adrenocortical tumor cortex metabolism over time].

Malignant adrenocortical tumors is serious oncological pathology, which without early diagnosis and radical, first of all, surgical treatment leads to death. The authors have analyzed the treatment results of 216 patients with adrenocortical carcinomas, which were in clinic during 1968-2002. The tumors were 32.

[Malignant hormonally inactive adrenal tumors: aspects of diagnosis and treatment].

Application of computer tomography (CT) and other modern methods of topic diagnosis have permitted to reveal "silent" adrenal tumors more frequently. To conduct a timely and radical treatment it is necessary to estimate the stage of malignancy and hormonal activity of these tumors. There were analyzed the results of treatment of 90 patients with malignant hormonally--inactive adrenal tumor.

[Treatment results in adrenal cortex malignant tumors ].

Malignant tumor of adrenal cortex without early diagnosis and radical surgical treatment is fatal. The results of treatment of 216 patients with adrenocortical carcinoma treated in 1968-2002, which is 32.6% of all the patients with tumors of adrenal cortex treated in the clinic were analyzed.