Lycopene prevents development of steatohepatitis in experimental nonalcoholic steatohepatitis model induced by high-fat diet.

We investigated the preventive effect of lycopene on nonalcoholic steatohepatitis-induced by high-fat diet in rats. Forty male Sprague-Dawley rats were divided into 4 groups. They were fed standard diet, high-fat diet (HFD), high-fat diet plus lycopene at a dose of 2 mg/kg body weight and the high-fat diet lycopene at a dose of 4 mg/kg BW for a period of 6 weeks.

[Biliary fasciolosis: a report of three cases diagnosed by ERCP].

Fasciola hepatica is an endemic parasite in Turkey. Chronic Fasciola hepatica infestation is known to cause biliary obstruction and inflammation. Also, biliary fasciolosis may be asymptomatic.

Fasciola hepatica case with hemobilia.

Fasciola hepatica (FH) can lead to important hepatobiliary diseases. Here we present a case of hemobilia associated with biliary FH, which is quite a rare case. The 41-year-old patient, who underwent common bile duct exploration due to hemobilia, was found to have arterial bleeding associated with ulcer caused by a dead parasite in the common bile duct.

Preventive role of genistein in an experimental non-alcoholic steatohepatitis model.

Background And Aim: The aim of the present study was to evaluate the preventive role of genistein, a phytoestrogen with a wide variety of pharmacological effects, in an experimental non-alcoholic steatohepatitis (NASH) model.

Methods: Thirty-six Sprague-Dawley rats were divided into three groups. Group 1 (control) received only a standard rat diet, group 2 (placebo) was given a high fat diet (HFD) plus 0.

Epigallocatechin gallate attenuates experimental non-alcoholic steatohepatitis induced by high fat diet.

Background And Aim: In the present study, we examined the preventive role of epigallocatechin gallate (EGCG) in an experimental non-alcoholic steatohepatitis model induced by a high fat diet.

Methods: The study included 21 male Sprague-Dawley rats, which were equally divided into three groups. The first group was fed on a standard rat diet, the second group on a high fat diet (HFD), and the third group on a HFD + EGCG.

Protective role of genistein in acute liver damage induced by carbon tetrachloride.

Aim: In the present study, we investigated the protective effect of genistein in experimental acute liver damage induced by CCl4.

Method: Forty rats were equally allocated to 5 groups. The first group was designated as the control group (group 1).

Amelioration of steatohepatitis with pentoxifylline in a novel nonalcoholic steatohepatitis model induced by high-fat diet.

We sought to evaluate the effects of pentoxifylline (PTX) on steatohepatitis in a novel experimental nonalcoholic steatohepatitis (NASH) model induced by a high-fat diet (HFD). Thirty-three male Sprague-Dawley rats were randomly divided into 3 groups. The first group received only standard rat diet (control group); groups 2 (placebo group) and 3 were given HFD, ad libitum.

The levels of ghrelin, leptin, TNF-alpha, and IL-6 in liver cirrhosis and hepatocellular carcinoma due to HBV and HDV infection.

Background/aim: Malnutrition, a common problem in liver cirrhosis and HCC, may readily deteriorate the clinical functions with resultant poor prognosis. Beside the hyper catabolic state frequently encountered in chronic liver disease and HCC, anorexia and reduced food intake also worsen the malnutrition. The recently discovered peptide hormone ghrelin acts as a counterpart of leptin in regulation of food intake and fat utilization.

Patients' awareness of their rights in a developing country.

Aim: To determine the awareness of a regulation on patients' rights passed in 1998 in Turkey.

Methods: All hospitalized patients in the internal medicine and general surgery wards in three large hospitals during the study period were eligible for the study, which was performed in 2001 in the Denizli province, Turkey. The study group consisted of 166 patients.

Effects of a comprehensive educational program on quality of life and emotional issues of dementia patient caregivers.

The aim of this community-based pre-post interventional study was to investigate the effectiveness of a comprehensive educational program reinforced by an individualized component (CEPRIC) on problems likely to be experienced by caregivers of persons with Alzheimer's disease, as defined by the North American Nursing Diagnosis Association (NANDA). The Beck Depression Scale, Beck Anxiety Inventory, and the Duke scales were used to measure depression, anxiety, and quality of life, respectively. Sixty-four participants (32 caregiver-patient pairs) took part in the program.

Cost of Alzheimer's disease in a developing country setting.

Purpose: To evaluate the economic impact of AD in Denizli, Turkey.

Design And Methods: This observational study was conducted with 42 AD patients and their primary caregivers. During the initial interview, demographic data and medical histories were collected with questionnaires.

Compliance with hand hygiene and glove use in a university-affiliated hospital.

Objective: The hands of healthcare workers often transmit pathogens causing nosocomial infections. This study examined compliance with handwashing and glove use.

Setting: A university-affiliated hospital.

The effect of cold on the occurrence of bruising, haematoma and pain at the injection site in subcutaneous low molecular weight heparin.

The purpose of this study was to investigate the effect of local dry cold application on the occurrence of bruising, haematoma and pain at the injection site in subcutaneous low molecular weight heparin injections. The research involved 63 patients who had received 2 x 20 mg enoxaparine and who were divided into four treatment groups. In the first group, cold was not applied.