Solvate Complex LiAlCl·SO: Synthesis and Physical-Chemical Properties.

This work describes the synthesis of the LiAlCl·SO solvate complex and its properties. Its composition was determined using thermogravimetric analysis, Raman spectroscopy, and UV-vis spectroscopy. The specific ionic conductivity of LiAlCl·SO is 4.

Structure and Physicochemical Properties of Solutions of Lithium Polysulfides in Tetrasolvate of Lithium Perchlorate with Sulfolane Molecular Dynamics Modeling.

Lithium polysulfides are intermediate products formed during the discharge and charge of lithium-sulfur batteries and have good solubility in electrolyte solutions. Therefore, the properties and structure of solutions of lithium polysulfides in electrolyte solutions affect the energy characteristics of the lithium-sulfur battery. In this work, the structure and physicochemical properties (density, ionic conductivity, and self-diffusion coefficients) of solutions of lithium disulfide, tetrasulfide, and octasulfide in lithium perchlorate tetrasolvate with sulfolane in a wide range of concentrations (0.

Epistemic uncertainty challenges aging clock reliability in predicting rejuvenation effects.

Epigenetic aging clocks have been widely used to validate rejuvenation effects during cellular reprogramming. However, these predictions are unverifiable because the true biological age of reprogrammed cells remains unknown. We present an analytical framework to consider rejuvenation predictions from the uncertainty perspective.

Influence of Mechanical Loading on the Process of Tribochemical Action on Physicochemical and Biopharmaceutical Properties of Substances, Using Lacosamide as an Example: From Micronisation to Mechanical Activation.

Many physical and chemical properties of solids, such as strength, plasticity, dispersibility, solubility and dissolution are determined by defects in the crystal structure. The aim of this work is to study in situ dynamic, dispersion, chemical, biological and surface properties of lacosamide powder after a complete cycle of mechanical loading by laser scattering, electron microscopy, FR-IR and biopharmaceutical approaches. The SLS method demonstrated the spontaneous tendency toward surface-energy reduction due to aggregation during micronisation.

Neuronal travelling waves explain rotational dynamics in experimental datasets and modelling.

Spatiotemporal properties of neuronal population activity in cortical motor areas have been subjects of experimental and theoretical investigations, generating numerous interpretations regarding mechanisms for preparing and executing limb movements. Two competing models, representational and dynamical, strive to explain the relationship between movement parameters and neuronal activity. A dynamical model uses the jPCA method that holistically characterizes oscillatory activity in neuron populations by maximizing the data rotational dynamics.

DFT Model of Elemental Sulfur in Sulfolane Solutions.

The structure and the thermodynamic and optical (UV) properties of elemental sulfur solution in sulfolane (Sl) have been studied using density functional theory methods. The cyclic molecular form of sulfur (S "crown") was found using PBE1PBE/6-311+G(d,p) approximation in combination with a polarizable continuum model (the integral equation formalism variant) to exist in sulfolane medium as a Sl-S-Sl solvate. It has been theoretically established that sulfur can form stable (S) clusters in concentrated solutions.

Population dynamics and demographic history of Eurasian collared lemmings.

Background: Ancient DNA studies suggest that Late Pleistocene climatic changes had a significant effect on population dynamics in Arctic species. The Eurasian collared lemming (Dicrostonyx torquatus) is a keystone species in the Arctic ecosystem. Earlier studies have indicated that past climatic fluctuations were important drivers of past population dynamics in this species.

Theoretical Investigation of the Structure and Physicochemical Properties of Alkaline and Alkaline Earth Metal Perchlorate Solutions in Sulfolane.

To assess the possibility of using solutions of perchlorates of alkali and alkaline earth metals in sulfolane as electrolytes for electrochemical energy storage devices with metal negative electrodes, the physicochemical properties of 0.5 M solutions of Me(ClO) (Me = Li, Na, K, Mg, and Ca) in sulfolane were simulated by the method of molecular dynamics. The density, viscosity, conductivity, self-diffusion coefficients, and transport numbers are calculated.

Verb-Mediated Prediction in Bilingual Toddlers.

Prediction is an important mechanism for efficient language processing. It has been shown that as a part of sentence processing, both children and adults predict nouns based on semantically constraining verbs. Language proficiency is said to modulate prediction: the higher proficiency, the better the predictive skill.

[The food habits of women as a factor of development of maternal obesity].

The article presents the results of analysis of diet habits of women in the Stavropol Krai. The study was carried out using single-stage structured interview quantitative survey. The respondent was guaranteed anonymity and the purpose of survey was explained.

The Oral Mucosa Status and the Correlation between the Functional Parameters and the Level of Nitric Oxide Metabolites in Saliva among Patients with GERD.

The study involved 91 patients (48 women and 43 men), aged from 18 to 70 years with GERD. All patients underwent the clinical dental examination according to a single scheme including general clinical manifestations (nausea, single vomiting, belching, heartburn, pain in the epigastrium and around the navel, and poor appetite) and dental manifestations of GERD. The objective assessment of the dental status of the examined patients included the measurement of the functional parameters of the mixed saliva, buffer capacity (BC) of saliva, and the detection of the nitric oxide metabolites (NOx) content in saliva from the right parotid salivary gland ("SRPSG") and in blood serum using the indirect method based on the determination of the stable metabolites: nitrates and nitrites using the Griess reaction.

[The Clinical Value of no-Reflow Phenomenon in the Routing Operation of The Regional Vascular Center].

Coronary no-reflow phenomenon (CNR) is a complication of primary percutaneous coronary intervention (PCI). According to different reports, CNR occurs in 10 to 60 % of cases. Despite the long history of studying this phenomenon many issues remain unsolved.

Human Alphoid Artificial Chromosome as a Gene Therapy Vector for the Developing Hemophilia A Model in Mice.

Human artificial chromosomes (HACs), including the de novo synthesized alphoid-HAC, are a powerful tool for introducing genes of interest into eukaryotic cells. HACs are mitotically stable, non-integrative episomal units that have a large transgene insertion capacity and allow efficient and stable transgene expression. Previously, we have shown that the alphoid-HAC vector does not interfere with the pluripotent state and provides stable transgene expression in human induced pluripotent cells (iPSCs) and mouse embryonic stem cells (ESCs).

[Moscow Screening: Lung Cancer Screening With Low-Dose Computed Tomography].

For the first time in Moscow and Russia, a program of selective lung cancer screening has been implemented with a comprehensive approach, including organizational, management, medical, technical and educational aspects and quality control. Unique ultra-low-dose protocols (ultra-LDCT) have been developed to implement the screening program. These protocols allow performing high-quality chest computed tomography for lung nodule detection with an effective dose of less than 1 mSv.

[Consensus resolution on a modern view on the therapeutic and prophylactic effect of individual oral care products containing fluoride].

The purpose of the publication was to present the materials of the Expert Council Consensus on 'A Modern View on the Treatment and Preventive Effect of Fluoride Containing Personal Oral Care Products', which took place on April 21, 2019 in Moscow (Russia) with the support of the pharmaceutical company JSC GlaskoSmitKlein Helsker. During the work of the expert council, a solution was developed for the safe use of fluoride-containing oral hygiene products as part of fluoride prevention of dental caries. In the real conditions of everyday life, it is advisable for dentists to: use local fluoride-containing agents to know the concentration of fluoride in drinking water and in areas with low and optimal levels of it; recommend fluorides for daily use in small concentrations, for example, for children from 2 years of age to brush their teeth twice a day with fluoride toothpaste for at least 3 minutes; children up to 6 years old, when brushing their teeth once, use no more than a pea-size piece of toothpaste with 500 ppm of fluoride; toothpastes with fluoride concentration from 500 to 5000 ppm should be admitted depending on the risk level of caries development; rinses with a fluoride concentration of 0.

Functional Activity of Lymphocytes of Healthy Donors and Cancer Patients After Culturing with IL-2 and IL-15.

The study focused on activation of lymphocytes derived from healthy donors and cancer patients in the medium supplemented with IL-2 and IL-15 at low concentrations. We studied morphological features of cultured cells, their viability, and proliferative and functional activities during culturing for up to 14 days. In comparison with lymphocytes derived from cancer patients, white blood cells derived from healthy donors demonstrated a number of advantages under the given culturing conditions such as higher viability, greater proliferative activity, and the potency for earlier activation; moreover, during activation they secreted the anti-inflammatory cytokines IL-4 and IL-10 at greater concentrations.

What Influences Language Impairment in Bilingual Aphasia? A Meta-Analytic Review.

Patterns of language impairment in multilingual speakers with post-stroke aphasia are diverse: in some cases the language deficits are parallel, that is, all languages are impaired relatively equally, whereas in other cases deficits are differential, that is, one language is more impaired than the other(s). This diversity stems from the intricate structure of the multilingual language system, which is shaped by a complex interplay of influencing factors, such as age of language acquisition, frequency of language use, premorbid proficiency, and linguistic similarity between one's languages. Previous theoretical reviews and empirical studies shed some light on these factors, however no clear answers have been provided.

Soluble HLA-I and HLA-II Molecules Are Potential Prognostic Markers of Progression of Systemic and Local Inflammation in Patients with COPD.

Soluble molecules of the major histocompatibility complex play an important role in the development of various immune-mediated diseases. However, there is not much information on the participation of these proteins in the pathogenesis of chronic obstructive pulmonary disease (COPD). The aim of our work was to determine the content of soluble molecules of the major histocompatibility complex of classes I and II (sHLA-I and sHLA-II) in the exhaled breath condensate (EBC) and in the blood serum in patients with moderate to severe COPD during the exacerbation and stable phase.

[Sturge-Weber syndrome in children. Clinical features, diagnosis and approaches to therapy on the example of three clinical cases].

Sturge-Weber syndrome belongs to the group of phacomotoses and is characterized by a combined lesion of the skin, eyes, nervous system and internal organs. The clinical course of Sturge-Weber syndrome is quite diverse. Of particular interest in the practice of pediatric neurology and neurosurgery is the fact that 72-90% of patients present with epilepsy.

The Russian version of the Oxford Cognitive Screen: Validation study on stroke survivors.

Objective: The Oxford Cognitive Screen (OCS) is a screening tool for the assessment of poststroke deficits in attention, memory, praxis, language, and number processing. The goal of the present study was to develop a Russian version of the OCS (Rus-OCS) via translation of the original battery, its cultural and linguistic adaptations, and reporting preliminary findings on its psychometric properties.

Method: All parts of OCS were translated by native Russian-speaking neuropsychologists.

In situ impedance spectroscopy of filament formation by resistive switches in polymer based structures.

It is shown that the impedance spectroscopy allows identification of the resistive switching mechanisms in complex composite structures. This statement was demonstrated on an example of organic based sandwich structures with a modified polymer matrix as an active element. The impedance spectroscopy scanning was performed for a series of intermediate states formed within the switching process.

Preliminary validation study of the Russian Birmingham Cognitive Screen.

Introduction: The Birmingham Cognitive Screen (BCoS) is designed for use with individuals who have acquired language impairment following stroke. Our goal was to develop a Russian version of the BCoS (Rus-BCoS) by translating the battery following cultural and linguistic adaptations and establishing preliminary data on its psychometric properties.

Method: Fifty patients with left-hemisphere stroke were recruited, of whom 98% were diagnosed with mild to moderate aphasia.

[RESULTS OF DUST FACTOR IN COPPER PYROMETALLURGY].

The dust entering the air of the working zone of metallurgical shops was shown to be presented by a disintegration aerosols originating in crushing and transporting ore materials and condensation occurring in the course of smelting, converting and fire-refining copper. The overwhelming majority of the grains have a size of 2.1-5.

[Implementation of systemic approach to evaluation of carcinogenic jeopardy, exemplified by copper metallurgy].

The authors suggested scientific and methodic approaches based on hygienic and medical prophylactic technologies to define carcinogenically dangerous occupations with unacceptable level of occupational carcinogenous risk, to control oncogenesis predictors in these occupations, to diagnose early stages of oncologic diseases, to specify medical and prophylactic measures -aimed to decrease oncologic morbidity.

Site-specific (13) С/(12) С isotope abundance ratios in dicarboxylic oxyacids as characteristics of their origin.

Rationale: Recommendations of relevant international organizations controlling the quality of grape wines and beverages specify that only tartaric acids of grape origin can be introduced to achieve the required parameters. The development of methods for determining the origin of tartaric acid in grape wine is of great technological significance.

Methods: Organic dicarboxylic oxyacids were extracted from wines as barium salts.