Energy Transfer in CeTbF Nanoparticles-CTAB Shell-Chlorin e System.

Formation and electronic excitation energy transfer process in the nanosystem consisting of CeTbF nanoparticles, cetrimonium bromide (CTAB) surfactant, and chlorin e photosensitizer were studied. It was shown that chlorin e molecules bind to CeTbF NP in the presence of CTAB forming thus CeTbF NP-CTAB-chlorin e nanosystem. We consider that binding occurs via chlorin e embedding in the shell of CTAB molecules, formed around NP.

[Specific disturbances of psychomotor development in children with thymomegaly].

Ninety children, aged from 2 month to 3 years, with thymomegaly and 25 aged-matched controls were studied. Most children with thymomegaly had disturbances of psychomotor development. Depending on their types, the cohort of children was stratified into 4 subgroups: 1st - 36 patients (40%) with schizotypal signs; 2nd - 30 hyperactive children (33%); 3rd - 19 children with hyperthymia signs (21%); 4th - 5 normal children (6%).

[Peculiarities of dephosphorylation reaction catalyzed by purified protein tyrosine phosphatase CD45 from thymocytes of intact and exposed to ionising radiation rats].

This paper is devoted to analysis of parameters of catalytical activity of CD45, the major transmembrane proteintyrosine phosphatase (PTP-ase) of the lymphocytes, isolated from plasma membranes of thymocytes of control and 0.5 Gy irradiated rats. CD45 catalytic features were evaluated using 0.

[Regulation of secretory processes in parietal cells in the different stomach pathologies].

This review deals with the analysis of the modern literature concerning molecular mechanisms of secretory activity of gastric mucosa cells and their importance during development of different pathologies. Gastric acid secretion is regulated by paracrine, endocrine and neural systems. The result of these systems functioning at the molecular level is signal transduction pathways activation by histamine, acetylcholine, gastrin and other mediators.

[Detection of mycoplasma antigens and immune complexes in sera of the children with bronchial asthma].

The study was targeted at revealing Mycoplasma pneumoniae (M.p.) and Mycoplasma hominis (M.

[Emergency care for acute wound entering of plutonium and americium into the body (real case)].

The article describes a case of slowly soluble plutonium and americium compounds entering human body via skin wound. During the wound healing, the authors followed features of biokinetics of the radioactive substances, determined the major route of their excretion, evaluated efficiency of surgical d-bridement and complexation medicine (pentacin). clinical and biophysicdata collected could serve to increase efficiency of urgent therapeutic and prophylactic measures aimed to individuals with wounds contaminated with radioactive substances.

[Use of lactusan for the correction of microecological intestinal disturbances in children].

The study demonstrated that lactusan (lactulose) could be used as an effective remedy in dysbacteriosis. Twenty four sick children aged 1 month to 15 years were examined. Administration of lactusan to 21 patients resulted in perceptible improvement of clinical symptoms, mainly to the cessation of diarrhea.

[Leukemia, lymphogranulomatosis and histiocytosis of Langerhans in children with a history of enlarged thymus gland].

The group consisted of 1056 children with enlarged thymus and a monitored catamnesis in 317 of 0.5-23 years. In 5 examinations in different periods after the diagnosis of enlarged thymus, haematological malignancies were diagnosed: acute lymphoblastic leukaemia (2 children), lymphogranulomatosis (1 child), chronic myeloid leukaemia (monocytic variant) and histiocytosis of Langerhans (1 child).

[The assessment of the interferon status of term newborns born to mothers with chronic nonspecific lung diseases].

The study involved 34 full-term newborn babies born by mothers with chronic nonspecific diseases of the lungs and 10 newborns born by mothers with the physiological course of pregnancy and parturition, the examinations being carried out in the early neonatal period. A lower capacity for production of endogenous and gamma-interferons at delivery and on day 6 of life as well as a higher incidence of intrauterine and postnatal infections were observed in the newborns of the first group. This indicated the necessity to consider such babies as a group at risk of developing neonatal complications.

[T and B components of the immune system in acute bronchopulmonary diseases in children with thymomegaly and without it].

The immune status was estimated comprehensively and indicators of the level I and II tests of T and B components of the immunity system were defined in 120 children with thymomegaly (group I), in 30 children with unenlarged thymus (group II), and in 40 practically healthy children with unestablished size of the thymus, with a favourable family and personal disease history, who had never fallen ill before the immunologic examination (group III). The children belonging to groups I and II were examined at the acute disease period, during convalescence and clinical wellbeing. It has been established that during the acute bronchopulmonary disease, the group I and II children manifested the same regularities of immune response to the action of an antigenic stimulus.

[Heterogeneity and polymorphism of the thymus hyperplasia syndrome in children in the first 3 years of life].

Sixteen years of observation over a large group of children with the syndrome of the enlarged thymus with the use of up-to-date methods of examining the CNS, immune, endocrine, neuroendocrine systems and the autopsy data allowed the heterogeneity and polymorphism of the given syndrome to be revealed. Both transitory and stable enlargement of the thymus may be observed. The syndrome of the stable-enlarged thymus is likely to be formed in the intrauterine period and postnatally as well.

[The production of immunomodulating polypeptides by the thymus during its acute (accidental) involution in children].

The content of the thymalin polypeptides in the thymus is studied in the course of the 1st to 4th stages of the acute thymus involution in children dying from noninfectious and infectious disease. The results obtained were compared to the level of the circulating thymic factor and the number of T- and 'O' lymphocytes in the circulating blood of children with identical diseases and control group of the same age. It is concluded that the acute involution of the thymus in children with non-infectious and acute infectious diseases results in the progressive decrease of the production by the thymus of the immunomodulating polypeptides (thymic hormones) which is restored in the period of recovery.

[New data on thymomegaly as a syndrome of congenital (primary) immunodeficiency].

Basing on a combined clinicomorphological investigation of the thymicolymphatic and neuroendocrine systems including measurements of blood thymic hormones and their levels in thymic tissue it is shown that congenital thymomegaly can be considered a dysfunction of the hypothalamo-hypophysial system. The dysfunction manifests with polyglandular endocrinopathy and congenital immunodeficiency related to the group of thymus-dependent immunodeficiencies. Thymomegaly is often coupled with congenital malformations.

[The pathogenesis of congenital thymus hyperplasia in children with immune defects].

Complex clinical and morphological studies were conducted into conditions of the thymus as well as of the lymphatic and neuro-endocrine systems in stillbirths and children up to five years of age. Thymic hormones in blood and thymic tissue were determined, as well. CTH, in most of these cases, was found to reflect dysfunction of the hypothalamic-hypophyseal system which eventually resulted in development of polyglandular endocrinopathy and congenital immune deficiency, primarily in the T-system.

[Subcellular distribution and properties of aldehyde dehydrogenase in the rat liver].

The subcellular distribution and certain properties of rat liver aldehyde dehydrogenase are investigated. The enzyme is shown to be localized in fractions of mitochondria and microsomes. Optimal conditions are chosen for detecting the aldehyde dehydrogenase activity in the mentioned fractions.