Dark-purple rice extract modulates gut microbiota composition in acetic acid- and indomethacin-induced inflammatory bowel disease in rats.

Ulcerative colitis (UC) and Crohn's disease (CD) are two major forms of inflammatory bowel disease (IBD). The disease has been linked with gut microbiota dysbiosis in which the balance of commensal communities is disrupted. Accumulating evidence demonstrates that treatment with biologically active compounds can modulate gut microbiota composition in animal models.

Efficacy of Generic Atorvastatin in a Real-World Setting.

Background: The ability of statins to reduce LDL-c plays an important role in both primary and secondary prevention of atherosclerotic cardiovascular diseases. Such treatment can often be costly, but using generic atorvastatin may reduce cost by up to US$2635. In addition, a previous 8-week study found that it exhibited comparable efficacy to the brand-name medication.

Comparative pharmacodynamic effects of two clopidogrel formulations under steady-state conditions in healthy Thai volunteers .

Objective: Clopidogrel is a commonly used antiplatelet aggregation agent. Compared with the reference clopidogrel product, most commercially available generic clopidogrel products contain different crystalline forms of clopidogrel. This study was aimed to compare the pharmacodynamics of a commonly used generic clopidogrel product in Thailand with the reference clopidogrel product under steady state conditions.

Effect of Andrographis paniculata Extract on Triglyceride Levels of the Patients with Hypertriglyceridemia: A Randomized Controlled Trial.

Background: Hypertriglyceridemia is one of the risk factors for cardiovascular disease, and reduction oftriglyceride (TG) level is recommended in clinical practice guidelines for the treatment. Recently, andrographolide, a main active compound of Andrographispaniculata has been shown to possess hypolipidemic effects in animals.

Objective: To investigate the TG-lowering effects of A.

Predictive risk factors of seizure-related injury in persons with epilepsy.

Objective: The clinical risk factors for seizure-related injuries (SRI) in adult persons with epilepsy (PWE) were studied and analyzed to develop a predictive model.

Methods: We enrolled 300 consecutive cases from three epilepsy clinics in Northeast, Thailand. Subjects were eligible if reported to have at least one seizure attack during the past 12 months.

Very high dose phenobarbital for refractory status epilepticus.

Background: Refractory status epilepticus (RSE), defined as status epilepticus that fails to respond to first, second and third-line therapy. The RSE is associated with high morbidity and mortality. Treatment guidelines of RSE give a spectrum of options, such as, continuous intravenous (i.

Basic knowledge of epilepsy among medical students.

Background: The medical students' knowledge about basic medical neuroscience in the preclinical level may be fragmented and incomplete.

Objective: Evaluate the knowledge of students prior to a lecture on epilepsy in clinical level.

Material And Method: One hundred ten fourth-year medical students' knowledge was accessed by a self-administered questionnaire.

Knowledge of epilepsy among teachers in Khon Kaen Province, Thailand.

Introduction: Epileptic patients face social stigmatization due to negative attitudes and incorrect knowledge on epilepsy.

Objectives: To evaluate knowledge of epilepsy among teachers in Khon Kaen province.

Material And Method: A self-administered questionnaire distributed to 102 teachers who attended the training lectures on epilepsy.