Publications by authors named "Kut F"
J Clin Immunol
November 2021
Article Synopsis
- Hyper-IgE syndromes and chronic mucocutaneous candidiasis are rare immunodeficiency disorders with genetic defects that have been increasingly characterized in recent studies.
- In a study of 275 patients, researchers identified 87 genetic mutations, achieving a diagnostic success rate of 28.4%, highlighting specific genes like DOCK8 and STAT3 associated with the conditions.
- The most common symptoms included high IgE levels, eczema, and respiratory infections, with a recommendation for targeted panel sequencing as a cost-effective screening tool for genetic diagnosis in patients with these disorders.
