Publications by authors named "Kusunoki K"

Introduction: Proximal femoral fractures are critically associated with increased risk of mortality and secondary fractures. Identifying prognosis predictors related to sagittal imbalance that are known to have negative impact on fracture risk and mortality is crucial. This study aimed to explore the relationship between various sagittal imbalance parameters and the prognosis of proximal femoral fractures to identify the most important prognostic indicators.

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Since the Act for Eliminating Discrimination against Persons with Disabilities was enacted in 2016, the number of students with disabilities in higher education institutions has increased significantly, creating a greater need for support. Developmental Coordination Disorder (DCD) often coexists with other neurodevelopmental disorders such as Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), and reading and writing difficulties; yet, awareness of DCD remains low. This study aimed to investigate the prevalence of DCD traits among Japanese higher education students and their relationship with ADHD, ASD, and reading and writing support needs A pilot study was conducted with 77 university students (mean age: 19.

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is a fast-growing leguminous tree that is widely cultivated in tropical areas such as Indonesia, Malaysia, Australia, and southern China. This tree has versatile utility in timber, furniture, and pulp production. Illumina sequencing of was conducted, and the raw data of 124,410,892 reads were filtered and assembled into 93,317 unigenes, with a total of 84,411,793 bases.

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  • The study focuses on developing a predictive model to diagnose anorectal cancer in patients with Crohn's disease (CD), which is often diagnosed at advanced stages and is challenging to treat.
  • Utilizing T2-weighted and T1-weighted MRI images, the research analyzed lesions in CD patients from Hyogo Medical University between 2009 and 2022.
  • The best-performing model was the Regularized Greedy Forest (RGF), achieving an impressive AUC of 0.944, with significant predictive features related to the texture and structure of the lesions identified through SHAP analysis.
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  • The comprehensive complication index (CCI) was evaluated against the Clavien-Dindo Classification (CDC) in patients who underwent surgery for ulcerative colitis (UC) to see which better predicts prolonged hospital stays.
  • A study included 588 patients, revealing a median length of stay (LOS) of 21 days, with 20.2% experiencing LOS greater than 30 days; the CCI identified independent risk factors for prolonged LOS.
  • The CCI model showed a better predictive ability (AUC of 0.86) compared to the CDC model (AUC of 0.82), suggesting that the CCI is a more effective tool for assessing complications in UC cases.
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Introduction: Laparoscopic surgery (LAP) is now recognized as the standard procedure for colorectal surgery. However, the standard surgery for ulcerative colitis (UC) is total proctocolectomy with ileal pouch anal anastomosis (IPAA), which may be an overly complex procedure to complete laparoscopically. We conducted this systematic review and meta-analysis to evaluate the efficacy as well as the advantages and disadvantages of LAP-IPAA in patients with UC stratified by the outcome of interest.

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Introduction: We aimed to investigate the effects of zinc deficiency and zinc medication in osteoporosis patients undergoing denosumab (DMAb).

Materials And Methods: This retrospective study was conducted at a single hospital. The participants were female osteoporosis patients visiting between April 2019 and April 2020.

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Introduction: We aimed to investigate secondary fracture and mortality rates, and risk factors in patients with proximal femoral fractures.

Materials And Methods: We conducted a multicenter prospective cohort study on female patients with proximal femoral fractures who underwent surgical treatment between April 2020 and March 2021. Postoperative follow-ups were performed at 6-, 12-, 18-, and 24-month intervals to determine the secondary fracture and mortality rates, and the risk factors and its influence were examined.

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Aims: Low-carbohydrate diets have become popular in the general community. The mutual relationship between the percentage of total energy intake from carbohydrates (CHO/E), glycemic control indices, and diabetes complications remains unclear.

Materials And Methods: This cross-sectional study included 177 patients with type 2 diabetes mellitus who regularly visited outpatient clinics.

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Introduction: Recently, fecal calprotectin has been identified and used as an assessment tool for the confirmation of disease activity in ulcerative colitis. Although a meta-analysis suggested the usefulness of fecal calprotectin for the assessment of pouchitis, the number of participants was still insufficient. Therefore, we prospectively measured fecal calprotectin levels during pouchoscopy and analyzed their associations with pouchitis.

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  • The study compared ulcerative colitis (UC) patients who had surgery for cancer/dysplasia with those who had surgery for refractory disease, examining their clinical characteristics and preoperative preparation for surgery.
  • Out of 443 UC surgical cases, 188 were for cancer/dysplasia, showing a rising trend (about 40% recently) in such cases; these patients also had longer disease duration and better nutritional status than those with refractory disease.
  • Findings revealed that cancer/dysplasia patients had lower severity of inflammation and significantly better nutritional factors, including weight, body mass index, serum albumin level, and prognostic nutrition index, compared to refractory UC patients.
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  • - This study aimed to explore the risk factors for recurrence in colorectal cancer associated with ulcerative colitis (UC-CRC) by analyzing 210 patients over 17 years, focusing on the 144 with stages I to III cancer.
  • - The findings revealed an overall recurrence rate of 12.5%, with a 5-year recurrence-free survival rate of 87.5%. Significant risk factors for recurrence included younger age at surgery, undifferentiated carcinoma, lymph node metastasis, and vascular invasion.
  • - It was concluded that young adult patients with advanced stage III UC-CRC tend to have a poorer prognosis compared to older adults, highlighting the importance of age as a risk factor in recurrence situations.
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Aim: The purpose of this study was to examine how the clinical characteristics, indications for surgery, and postoperative course of ulcerative colitis (UC) surgical patients changed before and after the introduction of biological agents.

Methods: Patients who underwent surgery for UC at Hyogo Medical University between 2000 and 2019 were included in the study; those who underwent surgery between 2000 and 2009 were included in the early group (n = 864), and those who underwent surgery between 2010 and 2019 were included in the late group (n = 834); each study factor was retrospectively compared.

Results: The mean ages at surgery (y) were 39.

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  • Colorectal carcinoma with enteroblastic and neuroendocrine differentiation is a rare subtype of colorectal cancers that express specific markers related to these two types of differentiation.
  • A recent case involved a 53-year-old male with long-standing ulcerative colitis, showing a tumor where most cells exhibited markers for enteroblastic features, while about half also showed neuroendocrine characteristics.
  • This case suggests that the unique dual differentiation may arise from neoplastic transformation in pluripotent stem cells in the context of chronic ulcerative colitis, marking a potentially novel finding in medical literature.
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Introduction: It is well known that the infectious complications and mortality rates are increased among elderly individuals with ulcerative colitis (UC) during medical treatment. However, there have been few reports on surgery in elderly individuals with UC, and some cohort studies have reported surgical complication and mortality rates similar to those in nonelderly individuals.

Methods: UC patients who underwent colectomy at the Hyogo College of Medicine between April 2012 and March 2020 were included in this study.

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From the viewpoint of the application of Ir-Ru alloys for the anode of proton exchange membrane fuel cells (PEMFCs), hydrogen peroxide (HO) generation and the hydrogen oxidation reaction (HOR) properties of well-defined Ir-Ru bimetallic surfaces (Ru/Ir(111)) have been investigated using scanning electrochemical microscopy (SECM). Using thermal inter-diffusion of vacuum-deposited Ru and substrate Ir atoms, the topmost surface atomic ratios of Ru/Ir(111) were controlled changing the substrate temperature () during the deposition of 1 monolayer (ML)-thick Ru. Low-energy ion scattering spectroscopy (LE-ISS) estimated the Ru/Ir ratio to be 1 : 1 ( = 673 K), 1 : 2 ( = 773 K), and 1 : 4 ( = 873 K).

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Purpose: We evaluated the influence of preoperative treatments with biologics on surgical morbidity in patients with Crohn's disease (CD).

Methods: We reviewed the surveillance data of patients with CD who underwent surgery between April 2018 and April 2021. The possible risk factors for morbidity were analyzed.

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Objectives: The appropriate and recommended delivery mode after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) has not been sufficiently evaluated. This study was designed to compare the delivery outcomes associated with cesarean section (CS) and vaginal delivery (VD) after IPAA.

Methods: We conducted a questionnaire-based survey of female patients who underwent IPAA for UC between July 1987 and May 2018.

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Objectives: Few reports are available on post-colectomy enteritis (PCE) with ulcerative colitis (UC), which can be severe and sometimes fatal. The clinical characteristics are unclear, and treatment and diagnosis protocols have not been established. We aimed to investigate the incidence, clinical characteristics, diagnostic criteria, and therapeutic outcomes of PCE in this study.

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Background: Cap polyposis (CP) is extremely rare in Japan, and there is no established cure. We report a case in which CP was improved by surgical treatment.

Case Presentation: A 48-year-old man was investigated at a local hospital because of diarrhea and bloody stools in 2018.

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Background & Aims: Myosteatosis is gathering attention as a feasible indicator for sarcopenia and increased risk of morbidity. However, the prognostic value of intramuscular adipose tissue content (IMAC) as an assessment method for myosteatosis remains controversial. The objectives of this study are to compare the prognostic value of intramuscular adipose tissue content (IMAC) with our newly-developed modified IMAC (mIMAC), and to assess the clinical significance of mIMAC in colorectal cancer (CRC) and gastric cancer (GC).

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Total proctocolectomy and an ileal pouch-anal anastomosis are recommended as the standard procedure for ulcerative colitis (UC)-colitis-associated cancer (CAC). However, several studies have reported the partial colectomy and endoscopic resection of UC-CAC in recent years. We present a surgical case of UC-CAC that was detected at a site that had not been diagnosed preoperatively, and we report potential problems of partial colectomy and endoscopic resection through this case.

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Background: Crohn's disease (CD) recurrence can occur not only at the site of anastomosis but also elsewhere in the bowel following an ileocolic resection (ICR) procedure. The aims of the present study were to assess long-term outcomes of a primary ICR procedure for CD in consecutive patients and examine the location of the reoperation causative lesion.

Methods: We examined cases of surgery with ICR initially performed at our institution.

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Background: The advanced lung cancer inflammation index is considered a useful prognostic biomarker of clinical outcomes in patients with malignancies. However, the prognostic value of the advanced lung cancer index in patients with colorectal cancer who underwent surgical resection remains unclear.

Objective: In this study, we evaluated the prognostic value of the advanced lung cancer index in patients with colorectal cancer.

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Expression pattern of aluminum (Al) tolerance genes is one of the major determinants of Al avoidance/tolerance within plant cultivars. We have performed transcriptome analysis of two contrasting (Al-tolerant, Disang; Al-sensitive, Joymati) cultivars of India's North Eastern region, an indica rice diversity hotspot, on exposure to excess Al treatment in acidic condition. Co-expression analysis and SNPs enrichment analysis proposed the role of both trans-acting and cis-acting polymorphisms in Al signaling in the Al-tolerant cultivar.

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