Publications by authors named "Kusuma Kumari Medooru"
Background: Oxidative stress, inflammation, and endothelial dysfunction represent a key triad for the development and progression of atherosclerosis. Due to chronic low-grade inflammation in chronic kidney disease (CKD), concentrations of various inflammatory, endothelial, and oxidative stress markers are elevated, increasing the risk of atherosclerosis. The present study was undertaken to compare oxidative stress, inflammation, and endothelial dysfunction in diabetic and nondiabetic CKD pre-dialysis patients.
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- The study examines how iron deficiency anemia (IDA) affects glycated hemoglobin (HbA1c) and glycated albumin (GA) levels, highlighting that IDA alters these biomarkers used for monitoring blood sugar control.
- It compares 30 nondiabetic patients with IDA to 30 healthy controls, finding significant differences in various blood parameters, including lower levels of iron and albumin and higher levels of glycemic indicators.
- The research suggests that low albumin levels in IDA may cause misleadingly high GA readings, indicating that GA should be interpreted cautiously in diabetic patients with IDA to avoid inappropriate treatment decisions and hypoglycemia risk.