Publications by authors named "Kushwaha S"

Background: The aim of the present study was to assess the egg quality, food safety, and hygiene practices in egg production among commercial and non-commercial farms.

Methods: A total of six, each commercial and non-commercial farm, were randomly selected form Barwala district, Panchkula, Haryana, for this study in 2019. A detailed interview on hygiene practices of farm workers was conducted.

View Article and Find Full Text PDF

Cr-doped VO thin film shows a huge resistivity change with controlled epitaxial strain at room temperature as a result of a gradual Mott metal-insulator phase transition with strain. This novel piezoresistive transduction principle makes Cr-doped VO thin film an appealing piezoresistive material. To investigate the piezoresistivity of Cr-doped VO thin film for implementation in MEMS sensor applications, the resistance change of differently orientated Cr-doped VO thin film piezoresistors with external strain change was measured.

View Article and Find Full Text PDF

Aseptic nonunion is prevalent in orthopedic practice, causing persistent pain and functional impairment. Humeral shaft fractures, accounting for 3-5% of all fractures, have nonunion rates of 2-33% in nonoperative and 5-10% in surgical management. This study, the largest case series on operative management of humeral shaft nonunion, examines surgical techniques and outcomes.

View Article and Find Full Text PDF

Aims: Sirolimus (SRL) mitigates cardiac allograft vasculopathy (CAV) progression and confers renal protection after heart transplantation (HT). However, its safety and efficacy in patients undergoing combined heart and kidney transplantation (HKT) are unclear. This study aimed to investigate the impact of conversion from calcineurin inhibitors (CNI) to SRL on CAV progression, renal function, and outcomes in HKT compared to isolated HT.

View Article and Find Full Text PDF

The International Telecommunication Union (ITU) predicts a substantial and swift increase in global mobile data traffic. The predictions suggest that this growth will vary from 390 EB (exabytes) to 5,016 EB (exabytes) from 2024 to 2030, accordingly. This work presents a new maximum capacity model (MCM) to improve the dynamic resource allocation, robust encryption, and Quality of Service (QoS) in 5G networks which helps to meet the growing need for high-bandwidth applications such as Voice over Internet Protocol (VoIP) and video streaming.

View Article and Find Full Text PDF

Background: Disparities in atrial fibrillation ablation rates have been studied previously, with a focus on either patient characteristics or systems factors, rather than geographic factors. The impact of electrophysiology (EP) centre practice patterns on ablation rates has not been well studied.

Methods: This population-based cohort study used linked administrative datasets covering physician billing codes, hospitalizations, prescriptions, and census data.

View Article and Find Full Text PDF

Shifting cultivation, an age-old agricultural practice, is a major factor in forest cover change across Southeast Asia, where repeated cycles of vegetation disturbance and regrowth lead to far-reaching environmental and socio-economic impacts. The present study aims to assess the spatio-temporal patterns of vegetation disturbance and regrowth caused by shifting cultivation in Tripura state of India, over the past three decades, utilizing temporal segmentation of time-series Landsat data. The study analyzed vegetation disturbance and regrowth patterns in a shifting cultivation landscape from 1991 to 2020 using normalized burn ratio trends through LandTrendr, validated by the TimeSync tool.

View Article and Find Full Text PDF

Sediment serves as a heavy metal store in the riverine system and provides information about the river's health. To understand the distribution of heavy metal content in the Ganga River basin (GRB), a total of 25-bed sediment and suspended particulate matter (SPM) samples were collected from 25 locations in December 2019. Bed sediment samples were analyzed for different physio-chemical parameters, along with heavy metals.

View Article and Find Full Text PDF
Article Synopsis
  • Non-coding RNAs, particularly MicroRNAs (miRNAs), play a crucial role in regulating gene expression by binding to specific mRNA targets, leading to gene silencing through degradation or translational inhibition.
  • * The research on miRNAs has enhanced our understanding of disease mechanisms and opened up potential therapeutic avenues, despite not yet having established clinical applications.
  • * A comprehensive grasp of miRNA biology is essential for their future use in diagnostics and treatments, encouraging ongoing studies to explore their roles in health and disease.
View Article and Find Full Text PDF
Article Synopsis
  • Genotyping is the analysis of an organism's DNA to determine its genetic traits and has applications in fields like agriculture, biomedicine, and conservation.
  • Genetic markers are categorized into random markers (like RFLP and AFLP) and functional markers (like SCoT and SRAP), with the latter being less utilized in animal science despite their advantages.
  • This review provides an overview of the different genotyping markers available, their benefits and limitations, and emphasizes the need for more use of functional markers in genetic research.
View Article and Find Full Text PDF

Background: Telemedicine holds immense potential to revolutionise healthcare delivery, particularly in resource-limited settings and for patients with chronic diseases. Despite proven benefits and policy reforms, the use of telemedicine remains low due to several patient, technology, and system-level barriers. Assisted telemedicine employs trained health professionals to connect patients with physicians, which can improve access and scope of telemedicine.

View Article and Find Full Text PDF

Glioblastoma multiforme (GBM) is the most prevalent and aggressive brain tumor found in adult humans with a poor prognosis and average survival of 14-15 months. In order to have a comprehensive understanding of proteome and identify novel therapeutic targets, this study focused mainly on the differentially abundant proteins (DAPs) of -induced GBM. is a constitutively active Ras mutant form essential for tumor progression by continuously activating signaling pathways leading to uncontrolled tumor growth.

View Article and Find Full Text PDF
Article Synopsis
  • The gut microbiome plays a crucial role in male reproductive health and infertility, acting as a system that interacts with the endocrine and immune systems.
  • Recent research on the gut-testis axis (GTA) suggests a connection between gut health and male reproduction, but some studies remain controversial.
  • Various factors, including diet and pollutants, can either disrupt or support gut microbiota, impacting hormone activities in reproduction and highlighting the need for further exploration of the GTA for potential therapies.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to explore how microRNAs (miRNAs) are expressed in Indian patients with tuberculosis (TB) and how their profiles differ between those with and without HIV coinfection.
  • Researchers analyzed serum exosomes from various groups (HIV-TB coinfected, extra-pulmonary TB, HIV-only, and pulmonary TB) using real-time PCR, identifying significant changes in miRNA levels.
  • Key findings indicated specific miRNAs were differentially expressed among the groups, which are linked to important biological pathways, highlighting their potential role as biomarkers for TB and its progression in Indian patients.*
View Article and Find Full Text PDF

Introduction: Giant cell tumor (GCT) is a benign locally aggressive tumor with features of frequent recurrence and metastatic potential. GCT of small bones of hand and feet is rare with high recurrence and potential to metastasis. This study aims to provide a case report of GCT of the first metatarsal treated with wide excision, autologous fibular grafting, and fixation with locking plate.

View Article and Find Full Text PDF

Background: Clinical drug trials are intricate, involving numerous stakeholders, substantial data, and stringent regulations. Traditional systems for recording, storing, and sharing trial data often face data integrity, transparency, security, and interoperability challenges. The utilization of blockchain technology has emerged as a transformative influence in various industries, and its potential within healthcare, particularly in clinical drug trials, is increasingly gaining recognition.

View Article and Find Full Text PDF
Article Synopsis
  • * A case study involved a 27-year-old male who experienced nail discoloration and tingling after using herbal bodybuilding supplements, revealing elevated arsenic levels and leading to a diagnosis of chronic arsenicosis with severe nail changes and early nerve damage.
  • * Chronic arsenicosis can cause various skin and nail conditions, such as pigment changes and hair loss; notable findings include total leukonychia, which hasn't been reported before as a result of arsenic exposure.
View Article and Find Full Text PDF

Aim: To investigate the possible role of systemic inflammatory markers (interleukin; IL-6, C-reactive protein; CRP, and albumin levels) in the development of Alzheimer's dementia (AD) and also find their association with the severity of disease.

Material And Methods: It was a cross-sectional study. Patients with Alzheimer's dementia (AD) and vascular dementia (VaD) from outpatient settings in tertiary care hospitals and non-demented controls (NDC) were recruited from the community.

View Article and Find Full Text PDF

An experiment was conducted to evaluate the compatibility of menatetrenone with selected pharmaceutical excipients. Fourier Transform Infrared Spectroscopy (FTIR) was used to assess drug-excipient compatibility. The present research systematically investigates the FTIR spectrum of each chemical compound separately and their physical blends, analyzing for possible shifts, alterations or novel peak that may indicate chemical interactions.

View Article and Find Full Text PDF

Rapid global urbanization and economic growth have significantly increased solid waste volumes, with hazardous waste posing substantial health and environmental risks. Co-processing strategies for industrial solid and hazardous waste as alternative fuels highlight the importance of integrated waste management for energy and material recovery. This study identifies and characterizes solid and hazardous industrial wastes with high calorific values from various industrial processes at Nirma Industries Limited.

View Article and Find Full Text PDF

Glycoconjugate vaccines elicit robust anti-polysaccharide Ab response by recruiting T-cell help. Multiple doses of glycoconjugate vaccine are required to induce long-lasting immunity. The characteristics of anti-polysaccharide Ab response have been reported previously.

View Article and Find Full Text PDF

Background Achilles tendinopathy is a common overuse tendon injury, affecting athletes in running and similar sports. Repetitive overload of the Achilles tendon is the primary cause of inflammation, collagen degeneration, and tendon thickening. This study aims to investigate the efficacy of combining low-level laser therapy (LLLT) with eccentric exercises in treating midportion Achilles tendinopathy.

View Article and Find Full Text PDF

Purpose: This study aimed to develop a classifier using supervised machine learning to effectively assess the impact of clinical, demographical, and biochemical factors in accurately predicting the antiseizure medications (ASMs) treatment response in people with epilepsy (PWE).

Methods: Data was collected from 786 PWE at the Outpatient Department of Neurology, Institute of Human Behavior and Allied Sciences (IHBAS), New Delhi, India from 2005 to 2015. Patients were followed up at the 2nd, 4th, 8th, and 12th month over the span of 1 year for the drugs being administered and their dosage, the serum drug levels, the frequency of seizure control, drug efficacy, the adverse drug reactions (ADRs), and their compliance to ASMs.

View Article and Find Full Text PDF
Article Synopsis
  • Computational biology integrates computer science with biology to analyze complex biological data on a large scale and develop predictive models.* -
  • In the 21st century, computational resources and AI are crucial in biological sciences, aiding in drug design and vaccine development to enhance human and animal welfare.* -
  • This review article highlights key computational resources and AI tools in vaccine research while also addressing their applications and limitations in the development process.*
View Article and Find Full Text PDF