The complex circumstellar environment of supernova 2023ixf.

The early evolution of a supernova (SN) can reveal information about the environment and the progenitor star. When a star explodes in vacuum, the first photons to escape from its surface appear as a brief, hours-long shock-breakout flare, followed by a cooling phase of emission. However, for stars exploding within a distribution of dense, optically thick circumstellar material (CSM), the first photons escape from the material beyond the stellar edge and the duration of the initial flare can extend to several days, during which the escaping emission indicates photospheric heating.

The Association of Urolithiasis with Uricosuria, Uricemia and their Combination.

Background: There are conflicting data on the significance of hyperuricemia or hyperuricosuria in urolithiasis formation and on the need for medical treatment.

Objectives: To assess the significance of hyperuricemia or hyperuricosuria in urolithiasis formation, particularly when hyperuricemia occurs with normal uricosuria.

Methods: The electronic medical records of patients treated in Haifa and the Western Galilee district of Clalit Health Services, Israel, were retrospectively screened for diagnosis of nephrolithiasis or renal or urinary tract/bladder calculi between February 2014 and April 2019.

A 12.4-day periodicity in a close binary system after a supernova.

Neutron stars and stellar-mass black holes are the remnants of massive star explosions. Most massive stars reside in close binary systems, and the interplay between the companion star and the newly formed compact object has been theoretically explored, but signatures for binarity or evidence for the formation of a compact object during a supernova explosion are still lacking. Here we report a stripped-envelope supernova, SN 2022jli, which shows 12.

Stress overshoot, hysteresis, and the Bauschinger effect in sheared dense colloidal suspensions.

The mechanical nonlinear response of dense Brownian suspensions of polymer gel particles is studied experimentally and by means of numerical simulations. It is shown that the response to the application of a constant shear rate depends on the previous history of the suspension. When the flow starts from a suspension at rest, it exhibits an elastic response followed by a stress overshoot and then a plastic flow regime.

Computation and visualization of cell-cell signaling topologies in single-cell systems data using Connectome.

Single-cell RNA-sequencing data has revolutionized our ability to understand of the patterns of cell-cell and ligand-receptor connectivity that influence the function of tissues and organs. However, the quantification and visualization of these patterns in a way that informs tissue biology are major computational and epistemological challenges. Here, we present Connectome, a software package for R which facilitates rapid calculation and interactive exploration of cell-cell signaling network topologies contained in single-cell RNA-sequencing data.

Remote ischemic preconditioning improves tissue oxygenation in a porcine model of controlled hemorrhage without fluid resuscitation.

Remote ischemic preconditioning (RIPC) involves deliberate, brief interruptions of blood flow to increase the tolerance of distant critical organs to ischemia. This study tests the effects of limb RIPC in a porcine model of controlled hemorrhage without replacement therapy simulating an extreme field situation of delayed evacuation to definitive care. Twenty-eight pigs (47 ± 6 kg) were assigned to: (1) control, no procedure (n = 7); (2) HS = hemorrhagic shock (n = 13); and (3) RIPC + HS = remote ischemic preconditioning followed by hemorrhage (n = 8).

Wide-angle static and dynamic light scattering under shear.

We develop and characterize a wide angle static and dynamic light scattering under shear setup. The apparatus is suitable for the study of the structure and the dynamics of soft materials systems with a sub-micron characteristic length scale. The shear device consists in two parallel plates, and the optical setup allows us to perform light scattering measurements in any plane that contains the gradient of the velocity field direction.

Nontuberculous mycobacteria infections of peritoneal dialysis patients: A multicenter study.

Objectives: Nontuberculous mycobacteria (NTM) infections pose a diagnostic challenge in peritoneal dialysis (PD) patients. In this study, we sought to identify findings that are suggestive of NTM infection in PD adult patients.

Methods: All patients with NTM exit-site infection (ESI) with/without tunnel infection and peritonitis identified during the last decade in eight medical centers in Israel were included.

Novel self-fixation chest drain device tested in a swine model of pneumo-hemothorax.

Introduction: Thoracic injuries account for 20-25% of trauma-related deaths. In cases of pneumothorax the insertion of a chest tube is mandatory but associated with high complication rates particularly when inserted under difficult conditions. The C-Lant is a novel chest-tube insertion device that provides integrated double fixation capabilities and can be used by responders with minimal experience.

The ideal position of the peritoneal dialysis catheter is not always ideal.

Purpose: Peritoneal catheter dysfunction is a frequent complication of peritoneal dialysis (PD). Traditionally, dysfunction has been attributed to catheter malposition, but whether the location of the catheter tip in the small pelvis really determines proper function is unclear.

Methods: We reviewed 900 abdominal X-ray images of PD patients from a 7-year period in two PD units that use different catheter types (straight and Swan Neck Curled).

Sustainability of Supervised Toothbrushing in Israeli Nurseries - Teachers' Perspective.

Purpose: The national supervised toothbrushing programme was implemented in 2015-2016 among 3- to 4-year-old children attending 600 nurseries in Israel. The objectives of this study were to assess factors associated with sustainability of programme implementation, based on nursery teachers' attitudes towards the programme, beliefs in its success and willingness to continue it in in the future.

Materials And Methods: A phone survey was conducted among nursery teachers participating in the programme.

Dental status, visits, and functional ability and dietary intake of elderly in Israel.

Background: Epidemiological studies have shown deterioration in dental health accompanying the ageing process. Tooth loss increases with age. Chewing ability is closely correlated with number of natural teeth present: there is a threshold of 20-21 teeth, below which chewing ability declines.

The approximated cardiovascular reserve index complies with haemorrhage related hemodynamic deterioration pattern: A swine exsanguination model.

Background: To estimate the cardiovascular reserve we formulated the Cardiovascular Reserve Index (CVRI) based on physiological measurements. The aim of this study was to evaluate the pattern of CVRI in haemorrhage-related haemodynamic deterioration in an animal model simulating combat injury.

Methods: Data were collected retrospectively from a research database of swine exsanguination model in which serial physiological measurements were made under anesthesia in 12 swine of haemorrhagic injury and 5 controls.

Oral Health-Related Quality of Life in the Elderly in Israel--Results from the National Health and Nutrition Survey of the Elderly 2005-2006.

Purpose: To assess the oral health-related quality of life of the Israeli elderly.

Materials And Methods: Data were collected from a subsample of those interviewed for the cross-sectional Mabat Zahav National Health and Nutrition Survey of the Elderly, carried out in 2005 and 2006 by the Ministry of Health in Israel. In-person interviews were conducted in the interviewees' homes using a structured questionnaire which included 7 questions on subjective dental health status and the 14 questions of the Oral Health Impact Profile 14 (OHIP-14).

Prospective life cycle assessment of graphene production by ultrasonication and chemical reduction.

One promising future bulk application of graphene is as composite additive. Therefore, we compare two production routes for in-solution graphene using a cradle-to-gate lifecycle assessment focusing on potential differences in energy use, blue water footprint, human toxicity, and ecotoxicity. The data used for the assessment is based on information in scientific papers and patents.

Validation of a Hebrew version of the child-OIDP index, an oral health-related quality of life measure for children.

Purpose: Sociodental indicators assess to what extent oral conditions interfere with normal social functions and alter behaviour such as attending work or school, parenting or home chores. The child OIDP (oral impact on daily performance), a sociodental indicator developed by Adulyan and Sheiham, is easy to apply and has a scoring system that quantifies the effect both by extent and frequency. The purpose of this study was to adapt the child OIDP into Hebrew and evaluate its validity and reliability.

Transesophageal endoscopic myotomy for achalasia: recognizing potential pitfalls before clinical application.

Background: Laparoscopic Heller esophagomyotomy is the standard of care for achalasia treatment. This procedure, although effective, must be performed with the patient under general anesthesia and is associated with several serious potential complications. The authors aimed to develop a method of performing transesophageal endoscopic esophagomyotomy (TEEM) that would obviate the need for both general anesthesia and external incisions while offering lower intra- and postoperative complications.

Laparoscopic infrared imaging--the future vascular map.

Objective: One of the most significant limitations of laparoscopic surgery is the inability to achieve tactile assessment of structures during surgical dissection. Because blood vessels are naturally warmer than their surroundings, infrared (IR) detection can be highly effective in identifying and mapping out their course. In recent years, IR detection has been used successfully for this purpose in open surgery.

Efficient multilevel eigensolvers with applications to data analysis tasks.

Multigrid solvers proved very efficient for solving massive systems of equations in various fields. These solvers are based on iterative relaxation schemes together with the approximation of the "smooth" error function on a coarser level (grid). We present two efficient multilevel eigensolvers for solving massive eigenvalue problems that emerge in data analysis tasks.

Acute effects of peritoneal dialysis solutions in the mesenteric microcirculation.

Long-term peritoneal dialysis induces morphological changes that may lead to gradual functional impairment of the peritoneal membrane. These changes are characterized by progressive reduction in solute transport or ultrafiltration failure. The mechanism of the peritoneal response to dialysis fluids has not yet been fully elucidated.

Geometry of intensive scalar dissipation events in turbulence.

The maxima of the scalar dissipation rate in turbulence appear in the form of sheets and correspond to the potentially most intensive scalar mixing events. Their cross section extension determines a locally varying diffusion scale of the mixing process and extends the classical Batchelor picture of one mean diffusion scale. The distribution of the local diffusion scales is analyzed for different Reynolds and Schmidt numbers with a fast multiscale technique applied to very high-resolution simulation data.

A comparison between vocal reaction time and word recognition measures of children with APD and age-matched peers using auditory word discrimination test.

The purpose of this study was to investigate the possibility of improving speech recognition testing sensitivity in children with auditory processing disorders (APD) by incorporating response time measures. A group of children identified in a clinical setting as having APD was compared to an age-matched peer group using a vocal reaction time (VRT) format. The participants were between the ages of 5.