Publications by authors named "Kushi Kushekar"
Front Immunol
December 2021
Article Synopsis
- Immunological non-responders (INR) are people living with HIV who do not recover CD4 T cell levels despite effective treatment, leading to poorer health outcomes.
- Research shows INR have more gut-homing CD4 T cells in their blood compared to immunological responders (IR), and these cells tend to be more exhausted.
- The study indicates that the increased exhaustion of mucosal CD4 T cells in INR is linked to gut damage, suggesting that issues with T cell function and gut health contribute to their impaired immune response.
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