Publications by authors named "Kushal Konwar Sarma"

Beyond natural enzymes, the artificially synthesized nanozymes have attracted a significant interest as it can overcome the limitations of the former. Here, we report synthesis of shape controlled nanozymes showing proteolytic activity using Carica papaya L. (papaya) latex.

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The present study describes the fabrication of polyaniline-silk fibroin (PASF) nanocomposite-based nerve conduits and their subsequent implantation in a rat sciatic nerve injury model for peripheral nerve regeneration. This is the first in vivo study of polyaniline-based nerve conduits describing the safety and efficacy of the conduits in treating peripheral nerve injuries. The nanocomposite was synthesized by electrospinning a mixture of silk fibroin protein and polyaniline wherein the silk nanofibers were observed to be uniformly coated with polyaniline nanoparticles.

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Aim: Aim of the study was to evaluate the effect of isoflurane anesthesia on physiological parameters, assessment of anesthetic qualities, and economy of use of isoflurane in domestic chickens ().

Materials And Methods: In this study, 18 apparently healthy adult domestic chickens were selected randomly and divided into three groups. The birds were anesthetized by masked induction with isoflurane at a dose rate of 3.

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In the present data article we report the in vitro and in vivo biocompatibility of fabricated nerve conduits described in Das et al. [1]. Green synthesised gold nanoparticles (GNPs) were evaluated for their cytotoxicity in rat Schwann cells (SCTM41).

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Article Synopsis
  • A new silk-gold nanocomposite nerve conduit was tested on rats with severe sciatic nerve injuries, showing promising results after 18 months.
  • The conduit, made by electrospinning silk fibers coated with gold nanoparticles, encouraged the growth of Schwann cells and was non-toxic, leading to better nerve regeneration.
  • Pre-seeding the conduits with Schwann cells significantly improved myelination and nerve function, as evidenced by strong motor unit potentials and enhanced animal movement.
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